TY - JOUR
T1 - Zirconium-Based Metal-Organic Frameworks as Reusable Antibacterial Peroxide Carriers for Protective Textiles
AU - Ma, Kaikai
AU - Cheung, Yuk Ha
AU - Xie, Haomiao
AU - Wang, Xingjie
AU - Evangelopoulos, Michael
AU - Kirlikovali, Kent O.
AU - Su, Shengyi
AU - Wang, Xiaoliang
AU - Mirkin, Chad A.
AU - Xin, John H.
AU - Farha, Omar K.
N1 - Funding Information:
The authors acknowledge the financial support from the Army Research Office (W911NF1910340) and the Northwestern University Institute for Catalysis in Energy Processes (ICEP), funded by the DOE, Office of Basic Energy Sciences (Award Number DE-FG02- 03ER15457). This work made use of the J.B. Cohen X-ray Diffraction Facility supported by the MRSEC program of the National Science Foundation (DMR-1720139) at the Materials Re-search Center of Northwestern University. This work made use of Keck-II and EPIC facilities of the NUANCE Center at Northwestern University, which has received support from the Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF NNCI-1542205); the MRSEC pro-gram (NSF DMR-1720139) at the Materials Research Center; the International Institute for Nanotechnology (IIN); the Keck Foundation; and the State of Illinois, through the IIN. This work made use of the IMSERC at Northwestern University, which has received support from the NSF (CHE-1048773 and DMR-0521267); the State of Illinois and IIN. K.O.K. gratefully acknowledges support from the IIN Postdoctoral Fellowship and the Northwestern University International Institute for Nanotechnology. J.H.X. acknowledges the support from General Research Fund of the Research Grants Council of the Hong Kong SAR Government (GRF 15208420). M.E. was partially supported by the Alexander S. Onassis Public Benefit Foundation. The authors acknowledge Dr. Timur Islamoglu for the helpful discussion.
Publisher Copyright:
© 2023 American Chemical Society
PY - 2023/3/28
Y1 - 2023/3/28
N2 - Countries around the world have sought efficient protective coverings, including masks, gowns, and fabrics, for air purification to protect people against infectious diseases. However, the demand for significant quantities of disposable protective textiles poses a global challenge, especially when the production of protective gear is suspended due to COVID-19 outbreaks in factories and along supply lines. Therefore, the development of reusable, self-decontaminating protective masks and coverings loaded with disinfectants, such as antibacterial peroxide species, presents an attractive strategy to fight against bacteria risks. In this work, we incorporated persulfate ions, which serve as stable active peroxide precursors, into two porous zirconium-based metal-organic frameworks (Zr-MOFs), enabling these materials to act as regenerable reservoirs for the slow release of biocidal hydrogen peroxide upon hydrolysis by contact with humid air. Single-crystal X-ray diffraction studies reveal the two different coordination motifs for the persulfate ions, which can either bridge between two adjacent nodes or coordinate to a single node depending on both the node connectivity and the distances between open metal sites. The active peroxide precursors within the porous Zr-MOF carriers are stable during storage and easily regenerated once consumed. Importantly, these persulfate-loaded Zr-MOFs can be integrated onto textiles using a facile aqueous in-situ growth procedure, and these composites demonstrate potent and reusable biocidal activity against both Gram-negative bacteria and Gram-positive bacteria. Overall, this approach presents a viable strategy to develop robust protective textiles capable of rapidly deactivating pathogens.
AB - Countries around the world have sought efficient protective coverings, including masks, gowns, and fabrics, for air purification to protect people against infectious diseases. However, the demand for significant quantities of disposable protective textiles poses a global challenge, especially when the production of protective gear is suspended due to COVID-19 outbreaks in factories and along supply lines. Therefore, the development of reusable, self-decontaminating protective masks and coverings loaded with disinfectants, such as antibacterial peroxide species, presents an attractive strategy to fight against bacteria risks. In this work, we incorporated persulfate ions, which serve as stable active peroxide precursors, into two porous zirconium-based metal-organic frameworks (Zr-MOFs), enabling these materials to act as regenerable reservoirs for the slow release of biocidal hydrogen peroxide upon hydrolysis by contact with humid air. Single-crystal X-ray diffraction studies reveal the two different coordination motifs for the persulfate ions, which can either bridge between two adjacent nodes or coordinate to a single node depending on both the node connectivity and the distances between open metal sites. The active peroxide precursors within the porous Zr-MOF carriers are stable during storage and easily regenerated once consumed. Importantly, these persulfate-loaded Zr-MOFs can be integrated onto textiles using a facile aqueous in-situ growth procedure, and these composites demonstrate potent and reusable biocidal activity against both Gram-negative bacteria and Gram-positive bacteria. Overall, this approach presents a viable strategy to develop robust protective textiles capable of rapidly deactivating pathogens.
UR - http://www.scopus.com/inward/record.url?scp=85149412233&partnerID=8YFLogxK
U2 - 10.1021/acs.chemmater.2c03288
DO - 10.1021/acs.chemmater.2c03288
M3 - Journal article
AN - SCOPUS:85149412233
SN - 0897-4756
VL - 35
SP - 2342
EP - 2352
JO - Chemistry of Materials
JF - Chemistry of Materials
IS - 6
ER -