TY - JOUR
T1 - Which type of mind–body exercise is most effective in improving functional performance and quality of life in patients with Parkinson's disease? A systematic review with network meta-analysis
AU - Mustafaoglu, Rustem
AU - Ahmed, Ishtiaq
AU - Pang, Marco Y.C.
N1 - Funding Information:
The authors would like to thank those who responded to our email inquiry and provided the data for analysis.
Publisher Copyright:
© 2022, This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.
PY - 2022/12
Y1 - 2022/12
N2 - Background: Several studies have investigated the effect of mind–body exercise (MBE) on functional performance and health-related quality of life (HRQoL) in Parkinson’s disease (PD), but it is still very difficult for clinicians to make informed decision on the best mind–body exercise for PD. Purpose: We analyzed the relative efficacy of MBE (yoga, Tai-Chi, Pilates, Qigong, and dance) in improving functional performance and HRQoL in patients with PD. Methods: A systematic review of randomized controlled trials (RCTs) was performed using network meta-analysis (NMA), searching the following databases: Cochrane, Web of Science, and PubMed using specific keywords until December 28, 2021, assessing the effects of MBE on functional performance and HRQoL in patients with PD. Results: This review included 60 RCTs with 2037 participants. A ranking of MBE for modifying various aspects of functional performance and HRQoL was achieved. Pairwise NMA showed Pilates to be the most effective in improving functional mobility (MD: − 3.81; 95% CI (− 1.55, − 6.07) and balance performance (SMD: 2.83; 95% CI (1.87, 3.78). Yoga (MD: − 5.95; 95% CI (− 8.73, − 3.16) and dance (MD: − 5.87; 95% CI (− 8.73, − 3.01) to be the most effective in improving motor function, whereas Qigong (MD: 0.32; 95% CI (0.00, 0.64) was most effective in improving gait speed. Considering HRQoL, dance was found to be the most effective (SMD: − 0.36; 95% CI (− 0.70, -0.01). Conclusion: MBE should be considered an effective strategy for improving functional performance and HRQoL in patients with PD. The most effective MBE intervention varied with the functional performance domain. Dance was an effective exercise for improving HRQoL among people with PD. PROSPERO registration ID: CRD42022301030.
AB - Background: Several studies have investigated the effect of mind–body exercise (MBE) on functional performance and health-related quality of life (HRQoL) in Parkinson’s disease (PD), but it is still very difficult for clinicians to make informed decision on the best mind–body exercise for PD. Purpose: We analyzed the relative efficacy of MBE (yoga, Tai-Chi, Pilates, Qigong, and dance) in improving functional performance and HRQoL in patients with PD. Methods: A systematic review of randomized controlled trials (RCTs) was performed using network meta-analysis (NMA), searching the following databases: Cochrane, Web of Science, and PubMed using specific keywords until December 28, 2021, assessing the effects of MBE on functional performance and HRQoL in patients with PD. Results: This review included 60 RCTs with 2037 participants. A ranking of MBE for modifying various aspects of functional performance and HRQoL was achieved. Pairwise NMA showed Pilates to be the most effective in improving functional mobility (MD: − 3.81; 95% CI (− 1.55, − 6.07) and balance performance (SMD: 2.83; 95% CI (1.87, 3.78). Yoga (MD: − 5.95; 95% CI (− 8.73, − 3.16) and dance (MD: − 5.87; 95% CI (− 8.73, − 3.01) to be the most effective in improving motor function, whereas Qigong (MD: 0.32; 95% CI (0.00, 0.64) was most effective in improving gait speed. Considering HRQoL, dance was found to be the most effective (SMD: − 0.36; 95% CI (− 0.70, -0.01). Conclusion: MBE should be considered an effective strategy for improving functional performance and HRQoL in patients with PD. The most effective MBE intervention varied with the functional performance domain. Dance was an effective exercise for improving HRQoL among people with PD. PROSPERO registration ID: CRD42022301030.
KW - Complementary therapies
KW - Functional performance
KW - Pilates
KW - Tai-chi
KW - Yoga
UR - http://www.scopus.com/inward/record.url?scp=85137486239&partnerID=8YFLogxK
U2 - 10.1007/s13760-022-02070-4
DO - 10.1007/s13760-022-02070-4
M3 - Review article
C2 - 36056269
AN - SCOPUS:85137486239
SN - 0300-9009
VL - 122
SP - 1433
EP - 1446
JO - Acta Neurologica Belgica
JF - Acta Neurologica Belgica
IS - 6
ER -