Uncoupling proteins: Targets of endocrine disruptors?

T. Pawade; P. W.L. Ho; K. H.H. Kwok; A. C.Y. Chu; S. L. Ho; D. B. Ramsden

doi:10.1016/j.mce.2005.06.008

Uncoupling proteins: Targets of endocrine disruptors?

T. Pawade, P. W.L. Ho, K. H.H. Kwok, A. C.Y. Chu, S. L. Ho, D. B. Ramsden

Research output: Journal article publication › Journal article › Academic research › peer-review

5 Citations (Scopus)

Abstract

The roles of uncoupling proteins (UCPs) are discussed. Particular attention has been paid to the roles of UCP2 to UCP5 as agents mediating thermogenesis, and to the concept of limited or "mild" uncoupling as a means of reducing oxidative stress. The role of the endocrine system, thyroid hormones and catecholamines, in regulating expression of UCPs is also discussed.

Original language	English
Pages (from-to)	79-86
Number of pages	8
Journal	Molecular and Cellular Endocrinology
Volume	244
Issue number	1-2
DOIs	https://doi.org/10.1016/j.mce.2005.06.008
Publication status	Published - 1 Dec 2005
Externally published	Yes

Keywords

ATP
Electron transport
Oxidative phosphorylation
Uncoupling protein

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Endocrinology

More information

10.1016/j.mce.2005.06.008

Cite this

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title = "Uncoupling proteins: Targets of endocrine disruptors?",

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AU - Ho, P. W.L.

AU - Kwok, K. H.H.

AU - Chu, A. C.Y.

AU - Ho, S. L.

AU - Ramsden, D. B.

PY - 2005/12/1

Y1 - 2005/12/1

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AB - The roles of uncoupling proteins (UCPs) are discussed. Particular attention has been paid to the roles of UCP2 to UCP5 as agents mediating thermogenesis, and to the concept of limited or "mild" uncoupling as a means of reducing oxidative stress. The role of the endocrine system, thyroid hormones and catecholamines, in regulating expression of UCPs is also discussed.

KW - ATP

KW - Electron transport

KW - Oxidative phosphorylation

KW - Uncoupling protein

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EP - 86

JO - Molecular and Cellular Endocrinology

JF - Molecular and Cellular Endocrinology

IS - 1-2

ER -

Uncoupling proteins: Targets of endocrine disruptors?

Abstract

Keywords

ASJC Scopus subject areas

More information

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