Ultrahigh frequency ultrasound microbeam for biomedical applications

Kwok Ho Lam, Ying Li, Changyang Lee, Qifa Zhou, K. Kirk Shung

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

7 Citations (Scopus)

Abstract

Several 200-MHz lithium niobate (LN) single crystal single-element press-focused ultrasonic transducers were developed for biomedical applications. Micro-particle trapping experiments were carried out to demonstrate that the acoustic device can manipulate a single microbead as small as 5 μm within the range of hundreds of micrometers in distilled water. As the result suggests that the 200-MHz microbeam device is capable of manipulating particles two-dimensionally at the cellular level, the device was used for studying red blood cell (RBC) mechanical deformation. It was found that by attaching the trapped microbead to a RBC, the RBC could be stretched by moving the trapped microbead. This preliminary result demonstrates the acoustic microbeam may be promising tool for studying the RBC membrane elastic properties.
Original languageEnglish
Title of host publication2012 IEEE International Ultrasonics Symposium, IUS 2012
Pages1994-1997
Number of pages4
DOIs
Publication statusPublished - 1 Dec 2012
Externally publishedYes
Event2012 IEEE International Ultrasonics Symposium, IUS 2012 - Dresden, Germany
Duration: 7 Oct 201210 Oct 2012

Conference

Conference2012 IEEE International Ultrasonics Symposium, IUS 2012
Country/TerritoryGermany
CityDresden
Period7/10/1210/10/12

Keywords

  • biomedical
  • microbeam
  • Ultrasonic transducer

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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