Two ellagic acid glycosides from Gleditsia sinensis Lam. with antifungal activity on Magnaporthe grisea

Ligang Zhou; Duan Li; Weibo Jiang; Zhizhong Qin; Shuang Zhao; Minghua Qiu; Jianyong Wu

doi:10.1080/14786410701192702

Two ellagic acid glycosides from Gleditsia sinensis Lam. with antifungal activity on Magnaporthe grisea

Ligang Zhou, Duan Li, Weibo Jiang, Zhizhong Qin, Shuang Zhao, Minghua Qiu, Jianyong Wu

Research output: Journal article publication › Journal article › Academic research › peer-review

42 Citations (Scopus)

Abstract

Two ellagic acid glycosides were isolated by bioassay-guided fractionation from the antimicrobial ethyl acetate fraction of the ethanol extract from Gleditsia sinensis spines, and identified as 3-O-methylellagic acid-4′-(5″-acetyl)-α-L- arabinofuranoside (1) and 3-O-methylellagic acid-4′-O-α-L- rhamnopyranoside (2). Both compounds were isolated from this plant species for the first time, and 1 is a new compound. The two compounds showed significant antifungal activity against the spore germination of rice blast fungus Magnaporthe grisea, with an IC50 value of 13.56 μg mL-1for 1 and 16.14 μg mL-1for 2.

Original language	English
Pages (from-to)	303-309
Number of pages	7
Journal	Natural Product Research
Volume	21
Issue number	4
DOIs	https://doi.org/10.1080/14786410701192702
Publication status	Published - 1 May 2007

Keywords

Antifungal activity
Ellagic acid glycoside
Gleditsia sinensis Lam
Leguminosae
Spine

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Plant Science
Organic Chemistry

More information

10.1080/14786410701192702

Cite this

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title = "Two ellagic acid glycosides from Gleditsia sinensis Lam. with antifungal activity on Magnaporthe grisea",

abstract = "Two ellagic acid glycosides were isolated by bioassay-guided fractionation from the antimicrobial ethyl acetate fraction of the ethanol extract from Gleditsia sinensis spines, and identified as 3-O-methylellagic acid-4′-(5″-acetyl)-α-L- arabinofuranoside (1) and 3-O-methylellagic acid-4′-O-α-L- rhamnopyranoside (2). Both compounds were isolated from this plant species for the first time, and 1 is a new compound. The two compounds showed significant antifungal activity against the spore germination of rice blast fungus Magnaporthe grisea, with an IC50 value of 13.56 μg mL-1for 1 and 16.14 μg mL-1for 2.",

keywords = "Antifungal activity, Ellagic acid glycoside, Gleditsia sinensis Lam, Leguminosae, Spine",

author = "Ligang Zhou and Duan Li and Weibo Jiang and Zhizhong Qin and Shuang Zhao and Minghua Qiu and Jianyong Wu",

year = "2007",

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doi = "10.1080/14786410701192702",

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T1 - Two ellagic acid glycosides from Gleditsia sinensis Lam. with antifungal activity on Magnaporthe grisea

AU - Zhou, Ligang

AU - Li, Duan

AU - Jiang, Weibo

AU - Qin, Zhizhong

AU - Zhao, Shuang

AU - Qiu, Minghua

AU - Wu, Jianyong

PY - 2007/5/1

Y1 - 2007/5/1

N2 - Two ellagic acid glycosides were isolated by bioassay-guided fractionation from the antimicrobial ethyl acetate fraction of the ethanol extract from Gleditsia sinensis spines, and identified as 3-O-methylellagic acid-4′-(5″-acetyl)-α-L- arabinofuranoside (1) and 3-O-methylellagic acid-4′-O-α-L- rhamnopyranoside (2). Both compounds were isolated from this plant species for the first time, and 1 is a new compound. The two compounds showed significant antifungal activity against the spore germination of rice blast fungus Magnaporthe grisea, with an IC50 value of 13.56 μg mL-1for 1 and 16.14 μg mL-1for 2.

AB - Two ellagic acid glycosides were isolated by bioassay-guided fractionation from the antimicrobial ethyl acetate fraction of the ethanol extract from Gleditsia sinensis spines, and identified as 3-O-methylellagic acid-4′-(5″-acetyl)-α-L- arabinofuranoside (1) and 3-O-methylellagic acid-4′-O-α-L- rhamnopyranoside (2). Both compounds were isolated from this plant species for the first time, and 1 is a new compound. The two compounds showed significant antifungal activity against the spore germination of rice blast fungus Magnaporthe grisea, with an IC50 value of 13.56 μg mL-1for 1 and 16.14 μg mL-1for 2.

KW - Antifungal activity

KW - Ellagic acid glycoside

KW - Gleditsia sinensis Lam

KW - Leguminosae

KW - Spine

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U2 - 10.1080/14786410701192702

DO - 10.1080/14786410701192702

M3 - Journal article

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SN - 1478-6419

VL - 21

SP - 303

EP - 309

JO - Natural Product Research

JF - Natural Product Research

IS - 4

ER -

Two ellagic acid glycosides from Gleditsia sinensis Lam. with antifungal activity on Magnaporthe grisea

Abstract

Keywords

ASJC Scopus subject areas

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