Two ellagic acid glycosides from Gleditsia sinensis Lam. with antifungal activity on Magnaporthe grisea

Ligang Zhou, Duan Li, Weibo Jiang, Zhizhong Qin, Shuang Zhao, Minghua Qiu, Jianyong Wu

Research output: Journal article publicationJournal articleAcademic researchpeer-review

36 Citations (Scopus)

Abstract

Two ellagic acid glycosides were isolated by bioassay-guided fractionation from the antimicrobial ethyl acetate fraction of the ethanol extract from Gleditsia sinensis spines, and identified as 3-O-methylellagic acid-4′-(5″-acetyl)-α-L- arabinofuranoside (1) and 3-O-methylellagic acid-4′-O-α-L- rhamnopyranoside (2). Both compounds were isolated from this plant species for the first time, and 1 is a new compound. The two compounds showed significant antifungal activity against the spore germination of rice blast fungus Magnaporthe grisea, with an IC50 value of 13.56 μg mL-1for 1 and 16.14 μg mL-1for 2.
Original languageEnglish
Pages (from-to)303-309
Number of pages7
JournalNatural Product Research
Volume21
Issue number4
DOIs
Publication statusPublished - 1 May 2007

Keywords

  • Antifungal activity
  • Ellagic acid glycoside
  • Gleditsia sinensis Lam
  • Leguminosae
  • Spine

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Plant Science
  • Organic Chemistry

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