Two-dimensional surface plasmon resonance biosensor array based on phase-sensitive measurement

H. P. Ho; K. S. Chan; C. L. Wong; K. F. Lei; W. I. Li; Wing Cheung Law; S. Y. Wu; S. K. Kong; C. Lin

doi:10.1117/12.619180

Two-dimensional surface plasmon resonance biosensor array based on phase-sensitive measurement

H. P. Ho, K. S. Chan, C. L. Wong, K. F. Lei, W. I. Li, Wing Cheung Law, S. Y. Wu, S. K. Kong, C. Lin

Research output: Journal article publication › Conference article › Academic research › peer-review

4 Citations (Scopus)

Abstract

We report a 2-dimensional surface plasmon resonance (SPR) imaging array sensor based on differential phase measurement between p- and s-polarization. This parallel detection provides the advantage of high-throughput sensing, which is essential in recent biosensing technology. In the differential measurement approach, the signal (p) and reference (s) beams go through exactly identical optical path. This greatly improves the phase detection stability. In the present setup we use a low-cost imaging device and a simple data analysis program to perform the required arrayed sensing operation. The system demonstrates a refractive index resolution of 1×10-4RIU per degree phase change.

Original language	English
Article number	59270E
Pages (from-to)	1-10
Number of pages	10
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	5927
DOIs	https://doi.org/10.1117/12.619180
Publication status	Published - 1 Dec 2005
Externally published	Yes
Event	Plasmonics: Metallic Nanostructures and Their Optical Properties III - San Diego, CA, United States Duration: 31 Jul 2005 → 3 Aug 2005

Keywords

Biosensors
Imaging
Interference
Surface plasmon resonance

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

More information

10.1117/12.619180

Cite this

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abstract = "We report a 2-dimensional surface plasmon resonance (SPR) imaging array sensor based on differential phase measurement between p- and s-polarization. This parallel detection provides the advantage of high-throughput sensing, which is essential in recent biosensing technology. In the differential measurement approach, the signal (p) and reference (s) beams go through exactly identical optical path. This greatly improves the phase detection stability. In the present setup we use a low-cost imaging device and a simple data analysis program to perform the required arrayed sensing operation. The system demonstrates a refractive index resolution of 1×10-4RIU per degree phase change.",

keywords = "Biosensors, Imaging, Interference, Surface plasmon resonance",

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AU - Ho, H. P.

AU - Chan, K. S.

AU - Wong, C. L.

AU - Lei, K. F.

AU - Li, W. I.

AU - Law, Wing Cheung

AU - Wu, S. Y.

AU - Kong, S. K.

AU - Lin, C.

PY - 2005/12/1

Y1 - 2005/12/1

N2 - We report a 2-dimensional surface plasmon resonance (SPR) imaging array sensor based on differential phase measurement between p- and s-polarization. This parallel detection provides the advantage of high-throughput sensing, which is essential in recent biosensing technology. In the differential measurement approach, the signal (p) and reference (s) beams go through exactly identical optical path. This greatly improves the phase detection stability. In the present setup we use a low-cost imaging device and a simple data analysis program to perform the required arrayed sensing operation. The system demonstrates a refractive index resolution of 1×10-4RIU per degree phase change.

AB - We report a 2-dimensional surface plasmon resonance (SPR) imaging array sensor based on differential phase measurement between p- and s-polarization. This parallel detection provides the advantage of high-throughput sensing, which is essential in recent biosensing technology. In the differential measurement approach, the signal (p) and reference (s) beams go through exactly identical optical path. This greatly improves the phase detection stability. In the present setup we use a low-cost imaging device and a simple data analysis program to perform the required arrayed sensing operation. The system demonstrates a refractive index resolution of 1×10-4RIU per degree phase change.

KW - Biosensors

KW - Imaging

KW - Interference

KW - Surface plasmon resonance

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DO - 10.1117/12.619180

M3 - Conference article

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EP - 10

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

M1 - 59270E

T2 - Plasmonics: Metallic Nanostructures and Their Optical Properties III

Y2 - 31 July 2005 through 3 August 2005

ER -

Two-dimensional surface plasmon resonance biosensor array based on phase-sensitive measurement

Abstract

Keywords

ASJC Scopus subject areas

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