TRIF-dependent Toll-like receptor signaling suppresses Scd1 transcription in hepatocytes and prevents diet-induced hepatic steatosis

Keyphrases

• Hepatocytes 100%
• Receptor Signaling 100%
• Toll-like 100%
• Diet-induced 100%
• Hepatic Steatosis 100%
• Stearoyl-CoA Desaturase 1 (SCD1) 100%
• High-fat Diet 50%
• Adaptor 50%
• Inflammation 25%
• Interferon-β (IFN-β) 25%
• Liver Cancer 25%
• Innate Immunity 25%
• Lipid Accumulation 25%
• Disease Progression 25%
• Steatosis 25%
• Polyinosinic-polycytidylic Acid 25%
• Predisposing Factors 25%
• Myeloid Cells 25%
• Disease Spectrum 25%
• Interferon Regulatory Factor 3 (IRF3) 25%
• Non-alcoholic Fatty Liver Disease (NAFLD) 25%
• Lipogenesis 25%
• Palmitic Acid 25%
• Metabolic Function 25%
• Liver Cirrhosis 25%
• Transcriptional Regulator 25%
• Trif 25%
• TIR Domain 25%
• Desaturase 25%
• Stearoyl 25%
• Coenzyme A 25%
• Steatohepatitis 25%
• Stearoyl-coenzyme A Desaturase 25%
• Rate-limiting Enzyme 25%

Medicine and Dentistry

• Fatty Liver 100%
• Hepatocyte 100%
• Toll Like Receptor 100%
• Stearoyl-CoA 50%
• High Fat Food 50%
• Disease Exacerbation 25%
• Nonalcoholic Fatty Liver 25%
• Liver Cancer 25%
• Promoter Region 25%
• Lipid Storage 25%
• Polyinosinic Polycytidylic Acid 25%
• Disease Predisposition 25%
• Innate Immunity 25%
• Palmitic Acid 25%
• Liver Cirrhosis 25%
• Myeloid Cell 25%
• Interferon Regulatory Factor 3 25%
• Steatohepatitis 25%
• Steatosis 25%
• Lipogenesis 25%
• Interferon 25%
• Diseases 25%

Biochemistry, Genetics and Molecular Biology

• Toll-Like Receptor 100%
• Transcription 100%
• Hepatocyte 100%
• TRIF 100%
• Coenzyme A 40%
• Lipogenesis 20%
• Enzyme 20%
• Myeloid 20%
• Promoter Region 20%
• Lipid Storage 20%
• Innate Immunity 20%
• IRF3 20%
• Palmitic Acid 20%
• Interferon 20%