TOF-MRA using Multi-Oblique-Stack Acquisition (MOSA)

Ed X. Wu (Corresponding Author), Edward S. Hui, Jerry S. Cheung

Research output: Journal article publicationJournal articleAcademic researchpeer-review

2 Citations (Scopus)


Purpose: To alleviate the intrinsic limitation of current time-of-flight magnetic resonance angiography (TOF-MRA) techniques, which are insensitive to in-plane blood flow due to the flow saturation effect. Materials and Methods: A multi-oblique-stack acquisition (MOSA) technique was proposed in this study to tackle this TOF problem by acquiring two or more TOF image stacks bearing different orientations. The MOSA approach was evaluated in human brain MR angiograms by integrating it with the widely used multiple overlapping thin-slab acquisition (MOTSA) technique. Two TOF image sets in different orientations were acquired using MOTSA. They were combined pixel-by-pixel by taking the maximum intensity value. Maximum intensity projection (MIP) was then performed, and the resulting MRA quality was assessed. Results: The results demonstrated that MR angiograms obtained by MOSA-MOTSA were clearly improved compared to those acquired by conventional MOTSA in the same scan time. Conclusion: MOSA clearly demonstrates its advantage over conventional TOF acquisition in visualizing in-plane blood flows.

Original languageEnglish
Pages (from-to)432-436
Number of pages5
JournalJournal of Magnetic Resonance Imaging
Issue number2
Publication statusPublished - Aug 2007
Externally publishedYes


  • MRA
  • Multiple acquisitions
  • Multiple angles
  • Time-of-flight
  • Vessel enhancement

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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