TY - JOUR
T1 - The use of omic technologies applied to traditional Chinese medicine research
AU - Sánchez-Vidaña, Dalinda Isabel
AU - Rajwani, Rahim
AU - Wong, Man Sau
N1 - Publisher Copyright:
Copyright © 2017 Dalinda Isabel Sánchez-Vidaña et al.
PY - 2017/1/31
Y1 - 2017/1/31
N2 - Natural products represent one of the most important reservoirs of structural and chemical diversity for the generation of leads in the drug development process. A growing number of researchers have shown interest in the development of drugs based on Chinese herbs. In this review, the use and potential of omic technologies as powerful tools in the modernization of traditional Chinese medicine are discussed. The analytical combination from each omic approach is crucial for understanding the working mechanisms of cells, tissues, organs, and organisms as well as the mechanisms of disease. Gradually, omic approaches have been introduced in every stage of the drug development process to generate high-quality Chinese medicine-based drugs. Finally, the future picture of the use of omic technologies is a promising tool and arena for further improvement in the modernization of traditional Chinese medicine.
AB - Natural products represent one of the most important reservoirs of structural and chemical diversity for the generation of leads in the drug development process. A growing number of researchers have shown interest in the development of drugs based on Chinese herbs. In this review, the use and potential of omic technologies as powerful tools in the modernization of traditional Chinese medicine are discussed. The analytical combination from each omic approach is crucial for understanding the working mechanisms of cells, tissues, organs, and organisms as well as the mechanisms of disease. Gradually, omic approaches have been introduced in every stage of the drug development process to generate high-quality Chinese medicine-based drugs. Finally, the future picture of the use of omic technologies is a promising tool and arena for further improvement in the modernization of traditional Chinese medicine.
UR - http://www.scopus.com/inward/record.url?scp=85013387768&partnerID=8YFLogxK
U2 - 10.1155/2017/6359730
DO - 10.1155/2017/6359730
M3 - Review article
SN - 1741-427X
VL - 2017
JO - Evidence-based Complementary and Alternative Medicine
JF - Evidence-based Complementary and Alternative Medicine
M1 - 6359730
ER -