The Synthesis of Iron Oxide Nanoparticles via Seed-Mediated Process and its Cytotoxicity Studies

J. H. Huang; H. J. Parab; Ru Shi Liu; T. C. Lai; M. Hsiao; C. H. Chen; D. P. Tsai; Y. K. Hwu

doi:10.1007/978-3-540-92841-6_197

The Synthesis of Iron Oxide Nanoparticles via Seed-Mediated Process and its Cytotoxicity Studies

J. H. Huang
, H. J. Parab
, Ru Shi Liu
, T. C. Lai
, M. Hsiao
, C. H. Chen
, D. P. Tsai
, Y. K. Hwu

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

3 Citations (Scopus)

Abstract

The development of a seed-mediated growth method for synthesis of iron oxide nanoparticles with tunable size distribution and magnetic properties is reported. The detailed investigation of the size distribution of seed as well as iron oxide nanoparticles during the growth process has been carried out using transmission electron microscopy (TEM). It was observed that the distribution of size gradually becomes narrow with time via the intra-particle ripening process and Oswald ripening process. The monodispersed iron oxide nanoparticles with sizes between 5-10 nm were fabricated using this method by varying the experimental parameters. The magnetic nanoparticles showed well-defined superparamagnetic and blocking temperature due to the size effects in consistent with the TEM images. The thermogravimetric analyses exhibited the size-dependent weight loss of the magnetic nanoparticles. The in vitro cytotoxicity tests were also performed in order to determine the cell viability as a function of size and concentration of the magnetic nanoparticles. The as-prepared iron oxide nanoparticles showed biocompatibility and nontoxicity against the normal as well as cancerous cell lines.

Original language	English
Title of host publication	13th International Conference on Biomedical Engineering - ICBME 2008
Pages	802-805
Number of pages	4
DOIs	https://doi.org/10.1007/978-3-540-92841-6_197
Publication status	Published - Dec 2008
Externally published	Yes
Event	13th International Conference on Biomedical Engineering, ICBME 2008 - , Singapore Duration: 3 Dec 2008 → 6 Dec 2008

Publication series

Name	IFMBE Proceedings
Volume	23
ISSN (Print)	1680-0737

Conference

Conference	13th International Conference on Biomedical Engineering, ICBME 2008
Country/Territory	Singapore
Period	3/12/08 → 6/12/08

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cytotoxicity and biomaterial
FeO
Magnetite
Nanoparticles

ASJC Scopus subject areas

Bioengineering
Biomedical Engineering

More information

10.1007/978-3-540-92841-6_197

Cite this

Huang, J. H., Parab, H. J., Liu, R. S., Lai, T. C., Hsiao, M., Chen, C. H., Tsai, D. P., & Hwu, Y. K. (2008). The Synthesis of Iron Oxide Nanoparticles via Seed-Mediated Process and its Cytotoxicity Studies. In 13th International Conference on Biomedical Engineering - ICBME 2008 (pp. 802-805). (IFMBE Proceedings; Vol. 23). https://doi.org/10.1007/978-3-540-92841-6_197

@inproceedings{3432ce3acf814d7184d7732dbd841859,

title = "The Synthesis of Iron Oxide Nanoparticles via Seed-Mediated Process and its Cytotoxicity Studies",

abstract = "The development of a seed-mediated growth method for synthesis of iron oxide nanoparticles with tunable size distribution and magnetic properties is reported. The detailed investigation of the size distribution of seed as well as iron oxide nanoparticles during the growth process has been carried out using transmission electron microscopy (TEM). It was observed that the distribution of size gradually becomes narrow with time via the intra-particle ripening process and Oswald ripening process. The monodispersed iron oxide nanoparticles with sizes between 5-10 nm were fabricated using this method by varying the experimental parameters. The magnetic nanoparticles showed well-defined superparamagnetic and blocking temperature due to the size effects in consistent with the TEM images. The thermogravimetric analyses exhibited the size-dependent weight loss of the magnetic nanoparticles. The in vitro cytotoxicity tests were also performed in order to determine the cell viability as a function of size and concentration of the magnetic nanoparticles. The as-prepared iron oxide nanoparticles showed biocompatibility and nontoxicity against the normal as well as cancerous cell lines.",

keywords = "Cytotoxicity and biomaterial, FeO, Magnetite, Nanoparticles",

author = "Huang, \{J. H.\} and Parab, \{H. J.\} and Liu, \{Ru Shi\} and Lai, \{T. C.\} and M. Hsiao and Chen, \{C. H.\} and Tsai, \{D. P.\} and Hwu, \{Y. K.\}",

year = "2008",

month = dec,

doi = "10.1007/978-3-540-92841-6\_197",

language = "English",

isbn = "9783540928409",

series = "IFMBE Proceedings",

pages = "802--805",

booktitle = "13th International Conference on Biomedical Engineering - ICBME 2008",

note = "13th International Conference on Biomedical Engineering, ICBME 2008 ; Conference date: 03-12-2008 Through 06-12-2008",

}

Huang, JH, Parab, HJ, Liu, RS, Lai, TC, Hsiao, M, Chen, CH, Tsai, DP & Hwu, YK 2008, The Synthesis of Iron Oxide Nanoparticles via Seed-Mediated Process and its Cytotoxicity Studies. in 13th International Conference on Biomedical Engineering - ICBME 2008. IFMBE Proceedings, vol. 23, pp. 802-805, 13th International Conference on Biomedical Engineering, ICBME 2008, Singapore, 3/12/08. https://doi.org/10.1007/978-3-540-92841-6_197

The Synthesis of Iron Oxide Nanoparticles via Seed-Mediated Process and its Cytotoxicity Studies. / Huang, J. H.; Parab, H. J.; Liu, Ru Shi et al.
13th International Conference on Biomedical Engineering - ICBME 2008. 2008. p. 802-805 (IFMBE Proceedings; Vol. 23).

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

TY - GEN

T1 - The Synthesis of Iron Oxide Nanoparticles via Seed-Mediated Process and its Cytotoxicity Studies

AU - Huang, J. H.

AU - Parab, H. J.

AU - Liu, Ru Shi

AU - Lai, T. C.

AU - Hsiao, M.

AU - Chen, C. H.

AU - Tsai, D. P.

AU - Hwu, Y. K.

PY - 2008/12

Y1 - 2008/12

N2 - The development of a seed-mediated growth method for synthesis of iron oxide nanoparticles with tunable size distribution and magnetic properties is reported. The detailed investigation of the size distribution of seed as well as iron oxide nanoparticles during the growth process has been carried out using transmission electron microscopy (TEM). It was observed that the distribution of size gradually becomes narrow with time via the intra-particle ripening process and Oswald ripening process. The monodispersed iron oxide nanoparticles with sizes between 5-10 nm were fabricated using this method by varying the experimental parameters. The magnetic nanoparticles showed well-defined superparamagnetic and blocking temperature due to the size effects in consistent with the TEM images. The thermogravimetric analyses exhibited the size-dependent weight loss of the magnetic nanoparticles. The in vitro cytotoxicity tests were also performed in order to determine the cell viability as a function of size and concentration of the magnetic nanoparticles. The as-prepared iron oxide nanoparticles showed biocompatibility and nontoxicity against the normal as well as cancerous cell lines.

AB - The development of a seed-mediated growth method for synthesis of iron oxide nanoparticles with tunable size distribution and magnetic properties is reported. The detailed investigation of the size distribution of seed as well as iron oxide nanoparticles during the growth process has been carried out using transmission electron microscopy (TEM). It was observed that the distribution of size gradually becomes narrow with time via the intra-particle ripening process and Oswald ripening process. The monodispersed iron oxide nanoparticles with sizes between 5-10 nm were fabricated using this method by varying the experimental parameters. The magnetic nanoparticles showed well-defined superparamagnetic and blocking temperature due to the size effects in consistent with the TEM images. The thermogravimetric analyses exhibited the size-dependent weight loss of the magnetic nanoparticles. The in vitro cytotoxicity tests were also performed in order to determine the cell viability as a function of size and concentration of the magnetic nanoparticles. The as-prepared iron oxide nanoparticles showed biocompatibility and nontoxicity against the normal as well as cancerous cell lines.

KW - Cytotoxicity and biomaterial

KW - FeO

KW - Magnetite

KW - Nanoparticles

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SN - 9783540928409

T3 - IFMBE Proceedings

SP - 802

EP - 805

BT - 13th International Conference on Biomedical Engineering - ICBME 2008

T2 - 13th International Conference on Biomedical Engineering, ICBME 2008

Y2 - 3 December 2008 through 6 December 2008

ER -

The Synthesis of Iron Oxide Nanoparticles via Seed-Mediated Process and its Cytotoxicity Studies

Abstract

Publication series

Conference

UN SDGs

Keywords

ASJC Scopus subject areas

More information

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