The relationship between the theory of planned behavior and medication adherence in patients with epilepsy

Chung-Ying Lin, John A. Updegraff, Amir H. Pakpour

Research output: Journal article publicationJournal articleAcademic researchpeer-review

41 Citations (Scopus)


Purpose The aim of this study was to apply the theory of planned behavior (TPB) with two other factors (action planning and coping planning) to the medication adherence of adults with epilepsy. Methods We measured the elements of the theory of planned behavior (attitude, subjective norm, perceived behavioral control, and behavioral intention), action planning, and coping planning at baseline among adults with epilepsy (n = 567, mean ± SD age = 38.37 ± 6.71 years, male = 48.5%). Medication adherence was measured using the Medication Adherence Report Scale (MARS) and antiepileptic serum level at the 24-month follow-up. Structural equation modeling (SEM) examined three models relating TPB elements to medication adherence. Results Three SEM models all had satisfactory fit indices. Moreover, attitude, subjective norms, perceived behavioral control, and intention together explained more than 50% of the variance for medication adherence measured using MARS. The explained variance increased to 61.8% when coping planning and action planning were included in the model, with coping planning having greater association than action planning. In addition, MARS explained 3 to 5% of the objective serum level. Conclusion The theory of planned behavior is useful in understanding medication adherence in adults with epilepsy, and future interventions may benefit by improving such beliefs as well as beliefs about coping planning.
Original languageEnglish
Pages (from-to)231-236
Number of pages6
JournalEpilepsy and Behavior
Publication statusPublished - 1 Aug 2016


  • Epilepsy
  • Medication adherence
  • Structural equation modeling
  • Theory of planned behavior

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Behavioral Neuroscience


Dive into the research topics of 'The relationship between the theory of planned behavior and medication adherence in patients with epilepsy'. Together they form a unique fingerprint.

Cite this