The Prevalence of Depression and Its Association With Quality of Life Among Pregnant and Postnatal Women in China: A Multicenter Study

Hai Xin Bo, Yuan Yang, Dong Ying Zhang, Meng Zhang, Pei Hong Wang, Xiao Hua Liu, Li Na Ge, Wen Xuan Lin, Yang Xu, Ya Lan Zhang, Feng Juan Li, Xu Juan Xu, Hong He Wu, Todd Jackson, Gabor S. Ungvari, Teris Cheung, Yu Tao Xiang

Research output: Journal article publicationJournal articleAcademic researchpeer-review

1 Citation (Scopus)


Background: This study examined the prevalence of depressive symptoms (depression hereafter) and its association with quality of life (QOL) among pregnant and postnatal women in China.

 Methods: In this multi-center, cross-sectional study, 1,060 pregnant and postnatal women from eight hospitals were assessed. Depression and QOL were measured using the Edinburgh Postnatal Depression Scale and the World Health Organization Quality of Life Questionnaire - brief version, respectively. 

Results: The prevalence of depression was 7.45% (95% CI: 5.87–9.04%) in the sample. Women with depression had lower QOL in physical, psychological, social and environmental domains compared to those without. Women with physical comorbidities were more likely to suffer from depression (OR = 2.391, 95% CI = 1.384–4.130, P = 0.002). 

Conclusion: Due to its negative association with QOL, increased attention should be paid to depression in pregnant and postnatal women. Regular screening assessment and preventive measures should be adopted to reduce risk of depression in this population.

Original languageEnglish
Article number656560
JournalFrontiers in Psychiatry
Publication statusPublished - 1 Apr 2021


  • China
  • depression
  • postnatal period
  • pregnancy
  • prevalence

ASJC Scopus subject areas

  • Psychiatry and Mental health

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