The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use

Filip Kielar; Ga Lai Law; Elizabeth J. New; David Parker

doi:10.1039/b804369h

The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use

Filip Kielar
, Ga Lai Law
, Elizabeth J. New
, David Parker

Research output: Journal article publication › Journal article › Academic research › peer-review

65 Citations (Scopus)

Abstract

Introduction of different substituents at the 7-position of a sensitising azaxanthone group in a series of emissive Eu and Tb complexes can determine the intracellular uptake and distribution profile and may be linked to modulation of protein affinity.

Original language	English
Pages (from-to)	2256-2258
Number of pages	3
Journal	Organic and Biomolecular Chemistry
Volume	6
Issue number	13
DOIs	https://doi.org/10.1039/b804369h
Publication status	Published - 25 Jun 2008
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

More information

10.1039/b804369h

Cite this

@article{e6e0cba53abe463ea7e967fec37b0d23,

title = "The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use",

abstract = "Introduction of different substituents at the 7-position of a sensitising azaxanthone group in a series of emissive Eu and Tb complexes can determine the intracellular uptake and distribution profile and may be linked to modulation of protein affinity.",

author = "Filip Kielar and Law, \{Ga Lai\} and New, \{Elizabeth J.\} and David Parker",

year = "2008",

month = jun,

day = "25",

doi = "10.1039/b804369h",

language = "English",

volume = "6",

pages = "2256--2258",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

number = "13",

}

The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use. / Kielar, Filip; Law, Ga Lai; New, Elizabeth J. et al.
In: Organic and Biomolecular Chemistry, Vol. 6, No. 13, 25.06.2008, p. 2256-2258.

Research output: Journal article publication › Journal article › Academic research › peer-review

TY - JOUR

T1 - The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use

AU - Kielar, Filip

AU - Law, Ga Lai

AU - New, Elizabeth J.

AU - Parker, David

PY - 2008/6/25

Y1 - 2008/6/25

N2 - Introduction of different substituents at the 7-position of a sensitising azaxanthone group in a series of emissive Eu and Tb complexes can determine the intracellular uptake and distribution profile and may be linked to modulation of protein affinity.

AB - Introduction of different substituents at the 7-position of a sensitising azaxanthone group in a series of emissive Eu and Tb complexes can determine the intracellular uptake and distribution profile and may be linked to modulation of protein affinity.

UR - https://www.scopus.com/pages/publications/45449088932

U2 - 10.1039/b804369h

DO - 10.1039/b804369h

M3 - Journal article

C2 - 18563255

SN - 1477-0520

VL - 6

SP - 2256

EP - 2258

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 13

ER -

The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use

Abstract

ASJC Scopus subject areas

More information

Other files and links

Fingerprint

Cite this