The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use

Filip Kielar, Ga Lai Law, Elizabeth J. New, David Parker

Research output: Journal article publicationJournal articleAcademic researchpeer-review

63 Citations (Scopus)

Abstract

Introduction of different substituents at the 7-position of a sensitising azaxanthone group in a series of emissive Eu and Tb complexes can determine the intracellular uptake and distribution profile and may be linked to modulation of protein affinity.
Original languageEnglish
Pages (from-to)2256-2258
Number of pages3
JournalOrganic and Biomolecular Chemistry
Volume6
Issue number13
DOIs
Publication statusPublished - 25 Jun 2008
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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