The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use

Filip Kielar; Ga Lai Law; Elizabeth J. New; David Parker

doi:10.1039/b804369h

The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use

Filip Kielar, Ga Lai Law, Elizabeth J. New, David Parker

Research output: Journal article publication › Journal article › Academic research › peer-review

64 Citations (Scopus)

Abstract

Introduction of different substituents at the 7-position of a sensitising azaxanthone group in a series of emissive Eu and Tb complexes can determine the intracellular uptake and distribution profile and may be linked to modulation of protein affinity.

Original language	English
Pages (from-to)	2256-2258
Number of pages	3
Journal	Organic and Biomolecular Chemistry
Volume	6
Issue number	13
DOIs	https://doi.org/10.1039/b804369h
Publication status	Published - 25 Jun 2008
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1039/b804369h

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title = "The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use",

abstract = "Introduction of different substituents at the 7-position of a sensitising azaxanthone group in a series of emissive Eu and Tb complexes can determine the intracellular uptake and distribution profile and may be linked to modulation of protein affinity.",

author = "Filip Kielar and Law, {Ga Lai} and New, {Elizabeth J.} and David Parker",

year = "2008",

month = jun,

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doi = "10.1039/b804369h",

language = "English",

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publisher = "Royal Society of Chemistry",

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}

The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use. / Kielar, Filip; Law, Ga Lai; New, Elizabeth J. et al.
In: Organic and Biomolecular Chemistry, Vol. 6, No. 13, 25.06.2008, p. 2256-2258.

Research output: Journal article publication › Journal article › Academic research › peer-review

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AU - Parker, David

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DO - 10.1039/b804369h

M3 - Journal article

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The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use

Abstract

ASJC Scopus subject areas

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