The nature and extent of working memory dysfunction in schizophrenia

Xiao yan Cao, Zhi Li, Hugo M. Metcalfe, Tian xiao Yang, Shu ping Tan, Ya Wang, Xiao hong Hong, Zhan jiang Li, Xin Yu, Eric F.C. Cheung, David L. Neumann, David H.K. Shum, Raymond C.K. Chan (Corresponding Author)

Research output: Journal article publicationJournal articleAcademic researchpeer-review

3 Citations (Scopus)


This study aimed to examine verbal and visual-spatial working memory (WM) dysfunction in patients with schizophrenia. We compared 60 patients with schizophrenia with 57 healthy controls (matched for age, educational level, and IQ) on three WM tasks. Patients with schizophrenia performed significantly more poorly than healthy controls on verbal, visual, and spatial WM tests. Moreover, WM deficits were inversely associated with both the positive and negative symptoms of the patients. Taken together, these findings suggest that there are pervasive WM impairments in patients with schizophrenia. In addition, clinical features may play a significant role in the expression of WM deficits.

Original languageEnglish
Pages (from-to)175-182
Number of pages8
JournalPsyCh Journal
Issue number3
Publication statusPublished - Dec 2013


  • schizophrenia
  • spatial
  • verbal
  • working memory

ASJC Scopus subject areas

  • General Psychology


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