The nature and extent of working memory dysfunction in schizophrenia

Xiao yan Cao; Zhi Li; Hugo M. Metcalfe; Tian xiao Yang; Shu ping Tan; Ya Wang; Xiao hong Hong; Zhan jiang Li; Xin Yu; Eric F.C. Cheung; David L. Neumann; David H.K. Shum; Raymond C.K. Chan

doi:10.1002/pchj.30

The nature and extent of working memory dysfunction in schizophrenia

Xiao yan Cao, Zhi Li, Hugo M. Metcalfe, Tian xiao Yang, Shu ping Tan, Ya Wang, Xiao hong Hong, Zhan jiang Li, Xin Yu, Eric F.C. Cheung, David L. Neumann, David H.K. Shum, Raymond C.K. Chan (Corresponding Author)

Research output: Journal article publication › Journal article › Academic research › peer-review

3 Citations (Scopus)

Abstract

This study aimed to examine verbal and visual-spatial working memory (WM) dysfunction in patients with schizophrenia. We compared 60 patients with schizophrenia with 57 healthy controls (matched for age, educational level, and IQ) on three WM tasks. Patients with schizophrenia performed significantly more poorly than healthy controls on verbal, visual, and spatial WM tests. Moreover, WM deficits were inversely associated with both the positive and negative symptoms of the patients. Taken together, these findings suggest that there are pervasive WM impairments in patients with schizophrenia. In addition, clinical features may play a significant role in the expression of WM deficits.

Original language	English
Pages (from-to)	175-182
Number of pages	8
Journal	PsyCh Journal
Volume	2
Issue number	3
DOIs	https://doi.org/10.1002/pchj.30
Publication status	Published - Dec 2013

Keywords

schizophrenia
spatial
verbal
working memory

ASJC Scopus subject areas

General Psychology

More information

10.1002/pchj.30

Cite this

@article{40d9d8da68674a11adca641bc33dec0e,

title = "The nature and extent of working memory dysfunction in schizophrenia",

abstract = "This study aimed to examine verbal and visual-spatial working memory (WM) dysfunction in patients with schizophrenia. We compared 60 patients with schizophrenia with 57 healthy controls (matched for age, educational level, and IQ) on three WM tasks. Patients with schizophrenia performed significantly more poorly than healthy controls on verbal, visual, and spatial WM tests. Moreover, WM deficits were inversely associated with both the positive and negative symptoms of the patients. Taken together, these findings suggest that there are pervasive WM impairments in patients with schizophrenia. In addition, clinical features may play a significant role in the expression of WM deficits.",

keywords = "schizophrenia, spatial, verbal, working memory",

author = "Cao, {Xiao yan} and Zhi Li and Metcalfe, {Hugo M.} and Yang, {Tian xiao} and Tan, {Shu ping} and Ya Wang and Hong, {Xiao hong} and Li, {Zhan jiang} and Xin Yu and Cheung, {Eric F.C.} and Neumann, {David L.} and Shum, {David H.K.} and Chan, {Raymond C.K.}",

note = "Publisher Copyright: {\textcopyright} 2013 The Institute of Psychology, Chinese Academy of Sciences and Wiley Publishing Asia Pty Ltd.",

year = "2013",

month = dec,

doi = "10.1002/pchj.30",

language = "English",

volume = "2",

pages = "175--182",

journal = "PsyCh Journal",

issn = "2046-0260",

publisher = "John Wiley and Sons Inc.",

number = "3",

}

TY - JOUR

T1 - The nature and extent of working memory dysfunction in schizophrenia

AU - Cao, Xiao yan

AU - Li, Zhi

AU - Metcalfe, Hugo M.

AU - Yang, Tian xiao

AU - Tan, Shu ping

AU - Wang, Ya

AU - Hong, Xiao hong

AU - Li, Zhan jiang

AU - Yu, Xin

AU - Cheung, Eric F.C.

AU - Neumann, David L.

AU - Shum, David H.K.

AU - Chan, Raymond C.K.

PY - 2013/12

Y1 - 2013/12

N2 - This study aimed to examine verbal and visual-spatial working memory (WM) dysfunction in patients with schizophrenia. We compared 60 patients with schizophrenia with 57 healthy controls (matched for age, educational level, and IQ) on three WM tasks. Patients with schizophrenia performed significantly more poorly than healthy controls on verbal, visual, and spatial WM tests. Moreover, WM deficits were inversely associated with both the positive and negative symptoms of the patients. Taken together, these findings suggest that there are pervasive WM impairments in patients with schizophrenia. In addition, clinical features may play a significant role in the expression of WM deficits.

AB - This study aimed to examine verbal and visual-spatial working memory (WM) dysfunction in patients with schizophrenia. We compared 60 patients with schizophrenia with 57 healthy controls (matched for age, educational level, and IQ) on three WM tasks. Patients with schizophrenia performed significantly more poorly than healthy controls on verbal, visual, and spatial WM tests. Moreover, WM deficits were inversely associated with both the positive and negative symptoms of the patients. Taken together, these findings suggest that there are pervasive WM impairments in patients with schizophrenia. In addition, clinical features may play a significant role in the expression of WM deficits.

KW - schizophrenia

KW - spatial

KW - verbal

KW - working memory

UR - http://www.scopus.com/inward/record.url?scp=84956898579&partnerID=8YFLogxK

U2 - 10.1002/pchj.30

DO - 10.1002/pchj.30

M3 - Journal article

AN - SCOPUS:84956898579

SN - 2046-0260

VL - 2

SP - 175

EP - 182

JO - PsyCh Journal

JF - PsyCh Journal

IS - 3

ER -

The nature and extent of working memory dysfunction in schizophrenia

Abstract

Keywords

ASJC Scopus subject areas

More information

Other files and links

Fingerprint

Cite this