TY - JOUR
T1 - The efficacy of different forms of acupuncture for the treatment of nocturnal enuresis in children
T2 - A systematic review and meta-analysis
AU - Kannan, Priya
AU - Bello, Umar M.
N1 - Funding Information:
This work is supported by the start-up fund [1-ZE8G] for early-career academics at the Hong Kong Polytechnic University.
Publisher Copyright:
© 2021 Elsevier Inc.
PY - 2022/7/1
Y1 - 2022/7/1
N2 - Background: The efficacy of different forms of acupuncture for the treatment of nocturnal enuresis in children is not known. Objective: To determine the efficacy of different forms of acupuncture, such as manual acupuncture, laser/electroacupuncture, acupoint injection, and moxibustion, for the treatment of nocturnal enuresis. Methods: A literature search was conducted on Medline, EMBASE, Web of Science, CINAHL, PubMed, Physiotherapy Evidence Database, and Scopus from database inception to September 2020. The Cochrane risk of bias tool was utilised to evaluate the risk of bias in each included study. The quality of the evidence was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation tool. Results: Thirteen trials (n = 890) were included. Meta-analyses revealed significantly greater numbers of children reporting improved nocturnal enuresis in the moxibustion (p = 0.004), acupoint injection (p = 0.020), and laser acupuncture (p = 0.001) groups than in the control groups. Meta-analyses showed no significant differences in the numbers of children reporting the complete cure of nocturnal enuresis between laser acupuncture and desmopressin (p = 0.57). Conclusions: The review identified moxibustion, acupoint injections, and laser acupuncture as effective treatments for nocturnal enuresis in children. However, the evidence for these interventions is limited and of very-low-grade quality. The effects of laser acupuncture compared with desmopressin remain inconclusive.
AB - Background: The efficacy of different forms of acupuncture for the treatment of nocturnal enuresis in children is not known. Objective: To determine the efficacy of different forms of acupuncture, such as manual acupuncture, laser/electroacupuncture, acupoint injection, and moxibustion, for the treatment of nocturnal enuresis. Methods: A literature search was conducted on Medline, EMBASE, Web of Science, CINAHL, PubMed, Physiotherapy Evidence Database, and Scopus from database inception to September 2020. The Cochrane risk of bias tool was utilised to evaluate the risk of bias in each included study. The quality of the evidence was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation tool. Results: Thirteen trials (n = 890) were included. Meta-analyses revealed significantly greater numbers of children reporting improved nocturnal enuresis in the moxibustion (p = 0.004), acupoint injection (p = 0.020), and laser acupuncture (p = 0.001) groups than in the control groups. Meta-analyses showed no significant differences in the numbers of children reporting the complete cure of nocturnal enuresis between laser acupuncture and desmopressin (p = 0.57). Conclusions: The review identified moxibustion, acupoint injections, and laser acupuncture as effective treatments for nocturnal enuresis in children. However, the evidence for these interventions is limited and of very-low-grade quality. The effects of laser acupuncture compared with desmopressin remain inconclusive.
KW - Acupuncture
KW - Laser acupuncture
KW - Moxibustion
KW - Nocturnal enuresis
UR - http://www.scopus.com/inward/record.url?scp=85120814727&partnerID=8YFLogxK
U2 - 10.1016/j.explore.2021.11.008
DO - 10.1016/j.explore.2021.11.008
M3 - Review article
C2 - 34893441
AN - SCOPUS:85120814727
SN - 1550-8307
VL - 18
SP - 488
EP - 497
JO - Explore
JF - Explore
IS - 4
ER -