TY - JOUR
T1 - The Effects of Light Therapy on Sleep, Agitation and Depression in People With Dementia
T2 - A Systematic Review and Meta-analysis of Randomized Controlled Trials
AU - Fong, Kenneth N.K.
AU - Ge, Xiangyang
AU - Ting, K. H.
AU - Wei, Minchen
AU - Cheung, Hilda
N1 - Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This project was funded by the Innovation and Technology Fund – Mid-stream Research Programme for Universities (Grant No.: MRP/011/17X), Innovation and Technology Commission, Hong Kong SAR.
Publisher Copyright:
© The Author(s) 2023.
PY - 2023/3/16
Y1 - 2023/3/16
N2 - Objective: To evaluate the effects of light therapy on the alleviation of sleep disturbances, agitation and depression in people with dementia. Methods: A search was performed in PubMed, Medline, SCOPUS, Web of Science, EMBASE, CINAHL, Cochrane Library, for studies published between 2000 and 2021. Results: A total of 4315 articles were screened. Sixteen articles were eligible for this review and 11 randomized controlled studies were included in the meta-analysis. Light therapy had a significant effect on reducing the number of awakenings in sleep (n = 4; 95% CI = −.56, −.05; I2 = 0%; SMD = −.31) but was not significant in reducing the wake after sleep onset (n = 3; 95% CI = −.14,.59; I2 = 0%; SMD =.23), agitation (n = 4; 95% CI = −1.02,.45; I2 = 87%; SMD = −.28) and depression (n = 6; 95% CI = −.80,.40, I2 = 85%; SMD = −.20). Conclusion: Light therapy appeared to be more effective in terms of alleviating sleep disturbances, rather than reducing agitation and depression, but its long-term effects remain unclear.
AB - Objective: To evaluate the effects of light therapy on the alleviation of sleep disturbances, agitation and depression in people with dementia. Methods: A search was performed in PubMed, Medline, SCOPUS, Web of Science, EMBASE, CINAHL, Cochrane Library, for studies published between 2000 and 2021. Results: A total of 4315 articles were screened. Sixteen articles were eligible for this review and 11 randomized controlled studies were included in the meta-analysis. Light therapy had a significant effect on reducing the number of awakenings in sleep (n = 4; 95% CI = −.56, −.05; I2 = 0%; SMD = −.31) but was not significant in reducing the wake after sleep onset (n = 3; 95% CI = −.14,.59; I2 = 0%; SMD =.23), agitation (n = 4; 95% CI = −1.02,.45; I2 = 87%; SMD = −.28) and depression (n = 6; 95% CI = −.80,.40, I2 = 85%; SMD = −.20). Conclusion: Light therapy appeared to be more effective in terms of alleviating sleep disturbances, rather than reducing agitation and depression, but its long-term effects remain unclear.
KW - behavioral and psychological symptoms
KW - dementia
KW - light therapy
KW - sleep
UR - http://www.scopus.com/inward/record.url?scp=85150315478&partnerID=8YFLogxK
U2 - 10.1177/15333175231160682
DO - 10.1177/15333175231160682
M3 - Review article
C2 - 36924042
AN - SCOPUS:85150315478
SN - 1533-3175
VL - 38
JO - American Journal of Alzheimer's Disease and other Dementias
JF - American Journal of Alzheimer's Disease and other Dementias
ER -