The development of chitosan based microcapsules as delivery vehicles for orally administered daunorubicin

P. L. Lam, K. K.H. Lee, Y. W. Ho, R. S.M. Wong, S. W. Tong, C. H. Cheng, K. H. Lam, Cheuk On Tang, Z. X. Bian, R. Gambari, S. H.L. Kok, C. H. Chui

Research output: Journal article publicationJournal articleAcademic researchpeer-review

8 Citations (Scopus)

Abstract

This study reports the use of chitosan microcapsules for daunorubicin delivery via an oral route. The potential oral delivery of the daunorubicin/chitosan microcapsules was examined using an in vivo athymic nude mice xenograft model with Non-Hodgkin's lymphoma cells. Microencapsulated daunorubicin could be administered orally with tumour growth inhibition activity.
Original languageEnglish
Pages (from-to)14109-14114
Number of pages6
JournalRSC Advances
Volume4
Issue number27
DOIs
Publication statusPublished - 1 Jan 2014

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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