The application of organic electrochemical transistors in biosensors

Feng Yan; Peng Lin; Helen L.W. Chan

doi:10.1149/1.3481263

The application of organic electrochemical transistors in biosensors

Feng Yan, Peng Lin, Helen L.W. Chan

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

1 Citation (Scopus)

Abstract

Ion-sensitive properties of organic electrochemical transistors (OECT) based on Poly(3,4-ethylenedioxythiophene): poly(styrene sulfonic acid) (PEDOT:PSS) are systematically studied for the first time. The transfer curve (IDS∼ VG) of an OECT shifts to lower gate voltage horizontally with the increase of the concentration of cations, including H+, K+, Na+, Ca2+, and Al3+, in the electrolyte. Nernstian relationships between the shift of the gate voltage and the concentrations of the cations have been obtained. Cell-based biosensors with cancer cells cultivated on top of the OECTs have been studied. The activities of the cells under the effect of trypsin have been monitored by characterizing the OECTs. It has been found that the performance of the device is sensitive to the surface charge and the morphology of the attached cells due to the electrostatic interaction between the adherent cells and the active layer of the OECT.

Original language	English
Title of host publication	Thin Film Transistors 10, TFT 10
Pages	399-408
Number of pages	10
Volume	33
Edition	5
DOIs	https://doi.org/10.1149/1.3481263
Publication status	Published - 1 Dec 2010
Event	10th Symposium on Thin Film Transistor Technologies, TFT 10 - 218th ECS Meeting - Las Vegas, NV, United States Duration: 11 Oct 2010 → 15 Oct 2010

Conference

Conference	10th Symposium on Thin Film Transistor Technologies, TFT 10 - 218th ECS Meeting
Country/Territory	United States
City	Las Vegas, NV
Period	11/10/10 → 15/10/10

ASJC Scopus subject areas

General Engineering

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1149/1.3481263

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title = "The application of organic electrochemical transistors in biosensors",

abstract = "Ion-sensitive properties of organic electrochemical transistors (OECT) based on Poly(3,4-ethylenedioxythiophene): poly(styrene sulfonic acid) (PEDOT:PSS) are systematically studied for the first time. The transfer curve (IDS∼ VG) of an OECT shifts to lower gate voltage horizontally with the increase of the concentration of cations, including H+, K+, Na+, Ca2+, and Al3+, in the electrolyte. Nernstian relationships between the shift of the gate voltage and the concentrations of the cations have been obtained. Cell-based biosensors with cancer cells cultivated on top of the OECTs have been studied. The activities of the cells under the effect of trypsin have been monitored by characterizing the OECTs. It has been found that the performance of the device is sensitive to the surface charge and the morphology of the attached cells due to the electrostatic interaction between the adherent cells and the active layer of the OECT.",

author = "Feng Yan and Peng Lin and Chan, {Helen L.W.}",

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note = "10th Symposium on Thin Film Transistor Technologies, TFT 10 - 218th ECS Meeting ; Conference date: 11-10-2010 Through 15-10-2010",

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AU - Yan, Feng

AU - Lin, Peng

AU - Chan, Helen L.W.

PY - 2010/12/1

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N2 - Ion-sensitive properties of organic electrochemical transistors (OECT) based on Poly(3,4-ethylenedioxythiophene): poly(styrene sulfonic acid) (PEDOT:PSS) are systematically studied for the first time. The transfer curve (IDS∼ VG) of an OECT shifts to lower gate voltage horizontally with the increase of the concentration of cations, including H+, K+, Na+, Ca2+, and Al3+, in the electrolyte. Nernstian relationships between the shift of the gate voltage and the concentrations of the cations have been obtained. Cell-based biosensors with cancer cells cultivated on top of the OECTs have been studied. The activities of the cells under the effect of trypsin have been monitored by characterizing the OECTs. It has been found that the performance of the device is sensitive to the surface charge and the morphology of the attached cells due to the electrostatic interaction between the adherent cells and the active layer of the OECT.

AB - Ion-sensitive properties of organic electrochemical transistors (OECT) based on Poly(3,4-ethylenedioxythiophene): poly(styrene sulfonic acid) (PEDOT:PSS) are systematically studied for the first time. The transfer curve (IDS∼ VG) of an OECT shifts to lower gate voltage horizontally with the increase of the concentration of cations, including H+, K+, Na+, Ca2+, and Al3+, in the electrolyte. Nernstian relationships between the shift of the gate voltage and the concentrations of the cations have been obtained. Cell-based biosensors with cancer cells cultivated on top of the OECTs have been studied. The activities of the cells under the effect of trypsin have been monitored by characterizing the OECTs. It has been found that the performance of the device is sensitive to the surface charge and the morphology of the attached cells due to the electrostatic interaction between the adherent cells and the active layer of the OECT.

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DO - 10.1149/1.3481263

M3 - Conference article published in proceeding or book

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BT - Thin Film Transistors 10, TFT 10

T2 - 10th Symposium on Thin Film Transistor Technologies, TFT 10 - 218th ECS Meeting

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ER -

The application of organic electrochemical transistors in biosensors

Abstract

Conference

ASJC Scopus subject areas

UN SDGs

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