TATC: Predicting Alzheimer's disease with actigraphy data

Jia Li, Zhihui Lu, Yu Rong, Timothy Kwok, Helen Meng, Hong Cheng

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

42 Citations (Scopus)

Abstract

With the increase of elderly population, Alzheimer's Disease (AD), as the most common cause of dementia among the elderly, is affecting more and more senior people. It is crucial for a patient to receive accurate and timely diagnosis of AD. Current diagnosis relies on doctors' experience and clinical test, which, unfortunately, may not be performed until noticeable AD symptoms are developed. In this work, we present our novel solution named time-aware TICC and CNN (TATC), for predicting AD from actigraphy data. TATC is a multivariate time series classification method using a neural attention-based deep learning approach. It not only performs accurate prediction of AD risk, but also generates meaningful interpretation of daily behavior pattern of subjects. TATC provides an automatic, low-cost solution for continuously monitoring the change of physical activity of subjects in daily living environment. We believe the future deployment of TATC can benefit both doctors and patients in early detection of potential AD risk.

Original languageEnglish
Title of host publicationKDD 2018 - Proceedings of the 24th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining
PublisherAssociation for Computing Machinery
Pages509-518
Number of pages10
ISBN (Print)9781450355520
DOIs
Publication statusPublished - 19 Jul 2018
Externally publishedYes
Event24th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining, KDD 2018 - London, United Kingdom
Duration: 19 Aug 201823 Aug 2018

Publication series

NameProceedings of the ACM SIGKDD International Conference on Knowledge Discovery and Data Mining

Conference

Conference24th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining, KDD 2018
Country/TerritoryUnited Kingdom
CityLondon
Period19/08/1823/08/18

Keywords

  • Actigraphy data
  • Alzheimer's Disease
  • Attention
  • Circadian rhythm

ASJC Scopus subject areas

  • Information Systems
  • Software

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