Abstract
A new chiral ligand 6, 6′-dimethoxy-2, 2′-diaminobiphenyl was successfully prepared from 3-nitrophenol via iodination, Ullmann coupling, and reduction. The resolving reagent (2R, 3R)- or (2S, 3S)-2, 3-di(phenylaminoearbonyl)tartaric acid was prepared from commercially available tartaric acid in large scale and was used to resolve the racemic 6, 6′-dimethoxy-2, 2′-diaminobiphenyl. The chiral 6, 6′-dimethoxy-2, 2′-diaminobiphenyl obtained was proved to be enantiomerically pure.
Original language | English |
---|---|
Pages (from-to) | 794-799 |
Number of pages | 6 |
Journal | Chinese Journal of Chemistry |
Volume | 19 |
Issue number | 8 |
DOIs | |
Publication status | Published - 1 Jan 2001 |
Externally published | Yes |
Keywords
- 2′-diaminobiphenyl
- 6, 6′-dimethoxy-2
- Chiral
- Resolution
- Synthesis
ASJC Scopus subject areas
- Chemistry(all)