Synthesis of 3-cyanoindole derivatives mediated by copper(I) iodide using benzyl cyanide

On Ying Yuen, Pui Ying Choy, Wing Kin Chow, Wing Tak Wong, Fuk Yee Kwong

Research output: Journal article publicationJournal articleAcademic researchpeer-review

65 Citations (Scopus)


Copper-mediated direct and regioselective C3-cyanation of indoles using benzyl cyanide as the cyanide anion source is presented. A wide range of indoles undergo cyanation smoothly by employing a reaction system of copper(I) iodide under open-to-air vessels.
Original languageEnglish
Pages (from-to)3374-3378
Number of pages5
JournalJournal of Organic Chemistry
Issue number7
Publication statusPublished - 5 Apr 2013

ASJC Scopus subject areas

  • Organic Chemistry

Cite this