Synthesis and structure of an air-stable organoantimony complex and its use as a catalyst for direct diastereoselective Mannich reactions in water

Jun Xia, Renhua Qiu, Shuangfeng Yin, Xiaowen Zhang, Shenglian Luo, Chak Tong Au, Kai Xia, Wai Yeung Wong

Research output: Journal article publicationJournal articleAcademic researchpeer-review

31 Citations (Scopus)

Abstract

An air-stable organoantimony complex with a 5,6,7,12-tetrahydrodibenzo[c,f][1,5]azastibocine framework was synthesized, characterized, and found to exhibit high catalytic efficiency towards one-pot Mannich reaction with high diastereoselectivity in water. The catalyst can be recycled 10 times without showing any appreciable loss of efficiency. This catalytic system affords a simple and efficient approach for the synthesis of β-amino ketones.
Original languageEnglish
Pages (from-to)1487-1492
Number of pages6
JournalJournal of Organometallic Chemistry
Volume695
Issue number10-11
DOIs
Publication statusPublished - 15 May 2010
Externally publishedYes

Keywords

  • Catalyst
  • Diastereoselectivity
  • Direct Mannich reaction
  • Lewis acid
  • Organoantimony

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry
  • Materials Chemistry

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