Synthesis and structure evaluation of a novel cantharimide and its cytotoxicity on SK-Hep-1 hepatoma cells

Stanton Hon Lung Kok, Chung Hin Chui, Wing Sze Lam, Jien Chen, Fung Yi Lau, Raymond Siu Ming Wong, Gregory Yin Ming Cheng, Paul Bo San Lai, Thomas Wai Tong Leung, Michael Wing Yiu Yu, Cheuk On Tang, Albert Sun Chi Chan

Research output: Journal article publicationJournal articleAcademic researchpeer-review

37 Citations (Scopus)


A remarkable control of the potency of cantharimide is described based on the electronic properties of functional group and it exhibits a relatively less toxic effect to the non-malignant hematological disorder bone marrow cells.
Original languageEnglish
Pages (from-to)1155-1159
Number of pages5
JournalBioorganic and Medicinal Chemistry Letters
Issue number5
Publication statusPublished - 1 Mar 2007


  • 2-Aminobenzothiazole
  • Cantharimide
  • Neoplasm

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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