Synergistic mediation of tumor signaling pathways in hepatocellular carcinoma therapy via dual-drug-loaded pH-responsive electrospun fibrous scaffolds

Keyphrases

• Antitumor Activity 33%
• Apoptosis 33%
• Area of Necrosis 33%
• Doxorubicin 100%
• Doxorubicin Release 33%
• Drug Loading 100%
• Dual Drug 100%
• Dual Drug Delivery System 33%
• Electrospun 33%
• Electrospun Scaffolds 100%
• Fibrous Scaffold 66%
• Hepatocellular Carcinoma Therapy 100%
• Implantable Scaffold 33%
• In Vivo Experiment 33%
• Inflammation 66%
• Inflammatory Cells 33%
• Initial Burst Release 33%
• Liver Tumor 33%
• Mesoporous Silica Particles 33%
• Oncogenesis 33%
• PH-responsive 100%
• PH-sensitive 33%
• Poly(L-lactide) 66%
• Public Attention 33%
• Residual Tumor 33%
• Sodium Bicarbonate 100%
• Tissue Defect 33%
• Tumor Recurrence 66%
• Tumor Resection 33%
• Tumor Signaling Pathways 100%
• Tumor-bearing nude Mice 33%
• Tumor-infiltrating 33%
• Tumorigenesis 33%

Medicine and Dentistry

• Antineoplastic Activity 25%
• Cancer Surgery 25%
• Carcinogenesis 50%
• Cell Signaling Pathway 100%
• Doxorubicin 100%
• Drug Delivery System 25%
• Hepatocellular Carcinoma 100%
• Ibuprofen 100%
• In Vitro 25%
• Inflammatory Cell 25%
• Lifespan 25%
• Liver Tumor 25%
• Necrosis 25%
• Neoplasm 100%
• Programmed Cell Death 25%
• Silicon Dioxide 25%
• Sodium Bicarbonate 75%
• Tumor Recurrence 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Antitumor Activity 25%
• Carcinogenesis 50%
• Dicarbonate 75%
• Doxorubicin 100%
• Drug Delivery System 25%
• Ibuprofen 100%
• Inflammation 50%
• Liver Cell Carcinoma 100%
• Liver Tumor 25%
• Mesoporous Silica 25%
• Necrosis 25%
• Neoplasm 100%
• Nude Mouse 25%
• Tumor Recurrence 50%