Synergistic effect of VEGF and BMP4 incorporated hydrogel in osteogenesis of non-decorticated posterior spinal fusion

J. C. Cheng; H. Y. Yeung; K. M. Lee; Y. M. Chiu; L. Qin; Xia Guo; P. Chow; Y. Tabata

Synergistic effect of VEGF and BMP4 incorporated hydrogel in osteogenesis of non-decorticated posterior spinal fusion

J. C. Cheng, H. Y. Yeung, K. M. Lee, Y. M. Chiu, L. Qin, Xia Guo, P. Chow, Y. Tabata

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

Abstract

The combined osteogenic effect of BMP4 and VEGF delivered by hydrogel in posterior spinal fusion was evaluated. For the study, 12 NZW rabbits divided into four groups and each animal in each group underwent standardized bilateral non-decorticated posterior intertransverse process spinal fusion at L5-L6 lumber spinal, and implanted with different grafting materials. It was observed that when BMP4 was added to the fusion site, the bone was formed only around the transverse process. It was suggested that the combination of VEGF and BMO4 with hydrogel opens a new channel for developing new composites for spinal fusion enhancement.

Original language	English
Title of host publication	Transactions - 7th World Biomaterials Congress
Pages	1554
Number of pages	1
Publication status	Published - 1 Dec 2004
Event	Transactions - 7th World Biomaterials Congress - Sydney, Australia Duration: 17 May 2004 → 21 May 2004

Conference

Conference	Transactions - 7th World Biomaterials Congress
Country/Territory	Australia
City	Sydney
Period	17/05/04 → 21/05/04

ASJC Scopus subject areas

General Engineering

Cite this

@inproceedings{b02d5b625d794759b04c88335c229226,

title = "Synergistic effect of VEGF and BMP4 incorporated hydrogel in osteogenesis of non-decorticated posterior spinal fusion",

abstract = "The combined osteogenic effect of BMP4 and VEGF delivered by hydrogel in posterior spinal fusion was evaluated. For the study, 12 NZW rabbits divided into four groups and each animal in each group underwent standardized bilateral non-decorticated posterior intertransverse process spinal fusion at L5-L6 lumber spinal, and implanted with different grafting materials. It was observed that when BMP4 was added to the fusion site, the bone was formed only around the transverse process. It was suggested that the combination of VEGF and BMO4 with hydrogel opens a new channel for developing new composites for spinal fusion enhancement.",

author = "Cheng, {J. C.} and Yeung, {H. Y.} and Lee, {K. M.} and Chiu, {Y. M.} and L. Qin and Xia Guo and P. Chow and Y. Tabata",

year = "2004",

month = dec,

day = "1",

language = "English",

isbn = "1877040193",

pages = "1554",

booktitle = "Transactions - 7th World Biomaterials Congress",

note = "Transactions - 7th World Biomaterials Congress ; Conference date: 17-05-2004 Through 21-05-2004",

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Synergistic effect of VEGF and BMP4 incorporated hydrogel in osteogenesis of non-decorticated posterior spinal fusion. / Cheng, J. C.; Yeung, H. Y.; Lee, K. M. et al.
Transactions - 7th World Biomaterials Congress. 2004. p. 1554.

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

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T1 - Synergistic effect of VEGF and BMP4 incorporated hydrogel in osteogenesis of non-decorticated posterior spinal fusion

AU - Cheng, J. C.

AU - Yeung, H. Y.

AU - Lee, K. M.

AU - Chiu, Y. M.

AU - Qin, L.

AU - Guo, Xia

AU - Chow, P.

AU - Tabata, Y.

PY - 2004/12/1

Y1 - 2004/12/1

N2 - The combined osteogenic effect of BMP4 and VEGF delivered by hydrogel in posterior spinal fusion was evaluated. For the study, 12 NZW rabbits divided into four groups and each animal in each group underwent standardized bilateral non-decorticated posterior intertransverse process spinal fusion at L5-L6 lumber spinal, and implanted with different grafting materials. It was observed that when BMP4 was added to the fusion site, the bone was formed only around the transverse process. It was suggested that the combination of VEGF and BMO4 with hydrogel opens a new channel for developing new composites for spinal fusion enhancement.

AB - The combined osteogenic effect of BMP4 and VEGF delivered by hydrogel in posterior spinal fusion was evaluated. For the study, 12 NZW rabbits divided into four groups and each animal in each group underwent standardized bilateral non-decorticated posterior intertransverse process spinal fusion at L5-L6 lumber spinal, and implanted with different grafting materials. It was observed that when BMP4 was added to the fusion site, the bone was formed only around the transverse process. It was suggested that the combination of VEGF and BMO4 with hydrogel opens a new channel for developing new composites for spinal fusion enhancement.

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M3 - Conference article published in proceeding or book

SN - 1877040193

SN - 9781877040191

SP - 1554

BT - Transactions - 7th World Biomaterials Congress

T2 - Transactions - 7th World Biomaterials Congress

Y2 - 17 May 2004 through 21 May 2004

ER -

Synergistic effect of VEGF and BMP4 incorporated hydrogel in osteogenesis of non-decorticated posterior spinal fusion

Abstract

Conference

ASJC Scopus subject areas

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