Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus

Shuihong Li; Qianqian Mou; Xinya Xu; Shuhua Qi; Polly H.M. Leung

doi:10.1098/rsos.172466

Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus

Shuihong Li, Qianqian Mou, Xinya Xu, Shuhua Qi, Polly H.M. Leung

Research output: Journal article publication › Journal article › Academic research › peer-review

10 Citations (Scopus)

Abstract

Penicillenol A2 (isolated from deep-sea fungus Penicillium biourgeianum DFFSCS023) has good antibacterial activity against methicillin-sensitive Staphylococcus aureus and in combination with beta-lactam antibiotics it could significantly decrease methicillin-resistant Staphylococcus aureus (MRSA) survival, which provides a novel treatment consideration for MRSA-caused infections.

Original language	English
Article number	172466
Journal	Royal Society Open Science
Volume	5
Issue number	5
DOIs	https://doi.org/10.1098/rsos.172466
Publication status	Published - 30 May 2018

Keywords

Methicillin-resistant Staphylococcus aureus
Penicillenols
Synergistic antibacterial activity

ASJC Scopus subject areas

General

More information

10.1098/rsos.172466

http://hdl.handle.net/10397/79273

Cite this

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abstract = "Penicillenol A2 (isolated from deep-sea fungus Penicillium biourgeianum DFFSCS023) has good antibacterial activity against methicillin-sensitive Staphylococcus aureus and in combination with beta-lactam antibiotics it could significantly decrease methicillin-resistant Staphylococcus aureus (MRSA) survival, which provides a novel treatment consideration for MRSA-caused infections.",

keywords = "Methicillin-resistant Staphylococcus aureus, Penicillenols, Synergistic antibacterial activity",

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AU - Mou, Qianqian

AU - Xu, Xinya

AU - Qi, Shuhua

AU - Leung, Polly H.M.

PY - 2018/5/30

Y1 - 2018/5/30

N2 - Penicillenol A2 (isolated from deep-sea fungus Penicillium biourgeianum DFFSCS023) has good antibacterial activity against methicillin-sensitive Staphylococcus aureus and in combination with beta-lactam antibiotics it could significantly decrease methicillin-resistant Staphylococcus aureus (MRSA) survival, which provides a novel treatment consideration for MRSA-caused infections.

AB - Penicillenol A2 (isolated from deep-sea fungus Penicillium biourgeianum DFFSCS023) has good antibacterial activity against methicillin-sensitive Staphylococcus aureus and in combination with beta-lactam antibiotics it could significantly decrease methicillin-resistant Staphylococcus aureus (MRSA) survival, which provides a novel treatment consideration for MRSA-caused infections.

KW - Methicillin-resistant Staphylococcus aureus

KW - Penicillenols

KW - Synergistic antibacterial activity

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U2 - 10.1098/rsos.172466

DO - 10.1098/rsos.172466

M3 - Journal article

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Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus

Abstract

Keywords

ASJC Scopus subject areas

More information

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