Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer: CHEST Guideline and Expert Panel Report

Alexandros Molasiotis; Jaclyn A. Smith; Peter Mazzone; Fiona Blackhall; Richard S. Irwin; Todd M. Adams; Kenneth W. Altman; Alan F. Barker; Surinder S. Birring; Fiona Blackhall; Donald C. Bolser; Louis Philippe Boulet; Sidney S. Braman; Christopher Brightling; Priscilla Callahan-Lyon; Brendan J. Canning; Anne B. Chang; Terrie Cowley; Paul Davenport; Satoru Ebihara; Ali A. El Solh; Patricio Escalante; Stephen K. Field; Dina Fisher; Cynthia T. French; Peter Gibson; Philip Gold; Cameron Grant; Anthony Harnden; Adam T. Hill; Richard S. Irwin; Peter J. Kahrilas; Karina A. Keogh; Kefang Lai; Andrew P. Lane; Mark A. Malesker; Peter Mazzone; Stuart Mazzone; Alex Molassiotis; M. Hassan Murad; Peter Newcombe; Huong Q. Nguyen; John Oppenheimer; Marcos I. Restrepo; Mark Rosen; Bruce Rubin; Jay H. Ryu; Jaclyn Smith; Susan M. Tarlo; Julie Turmel; Anne E. Vertigan; Miles M. Weinberger; Kelly Weir

doi:10.1016/j.chest.2016.12.028

Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer: CHEST Guideline and Expert Panel Report

Alexandros Molasiotis, Jaclyn A. Smith, Peter Mazzone, Fiona Blackhall, Richard S. Irwin, Todd M. Adams, Kenneth W. Altman, Alan F. Barker, Surinder S. Birring, Fiona Blackhall, Donald C. Bolser, Louis Philippe Boulet, Sidney S. Braman, Christopher Brightling, Priscilla Callahan-Lyon, Brendan J. Canning, Anne B. Chang, Terrie Cowley, Paul Davenport, Satoru EbiharaAli A. El Solh, Patricio Escalante, Stephen K. Field, Dina Fisher, Cynthia T. French, Peter Gibson, Philip Gold, Cameron Grant, Anthony Harnden, Adam T. Hill, Richard S. Irwin, Peter J. Kahrilas, Karina A. Keogh, Kefang Lai, Andrew P. Lane, Mark A. Malesker, Peter Mazzone, Stuart Mazzone, Alex Molassiotis, M. Hassan Murad, Peter Newcombe, Huong Q. Nguyen, John Oppenheimer, Marcos I. Restrepo, Mark Rosen, Bruce Rubin, Jay H. Ryu, Jaclyn Smith, Susan M. Tarlo, Julie Turmel, Anne E. Vertigan, Miles M. Weinberger, Kelly Weir

Research output: Journal article publication › Journal article › Academic research › peer-review

42 Citations (Scopus)

Abstract

We used a 2015 Cochrane systematic review, among other sources of evidence, to update the recommendations and suggestions of the American College of Chest Physicians (CHEST) 2006 guideline on this topic. Methods The CHEST methodologic guidelines and the Grading of Recommendations, Assessment, Development, and Evaluation framework were used. The Expert Cough Panel based their recommendations on data from the Cochrane systematic review on the topic, uncontrolled studies, case studies, and the clinical context. Final grading was reached by consensus according to the Delphi method. Results The Cochrane systematic review identified 17 trials of primarily low-quality evidence. Such evidence was related to both nonpharmacologic (cough suppression) and pharmacologic (demulcents, opioids, peripherally acting antitussives, or local anesthetics) treatments, as well as endobronchial brachytherapy. Conclusions Compared with the 2006 CHEST Cough Guideline, the current recommendations and suggestions are more specific and follow a step-up approach to the management of cough among patients with lung cancer, acknowledging the low-quality evidence in the field and the urgent need to develop more effective, evidence-based interventions through high-quality research.

Original language	English
Pages (from-to)	861-874
Number of pages	14
Journal	Chest
Volume	151
Issue number	4
DOIs	https://doi.org/10.1016/j.chest.2016.12.028
Publication status	Published - 1 Apr 2017

Keywords

cough
evidence-based medicine
guidelines
lung cancer

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine
Cardiology and Cardiovascular Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.chest.2016.12.028

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Molasiotis, A., Smith, J. A., Mazzone, P., Blackhall, F., Irwin, R. S., Adams, T. M., Altman, K. W., Barker, A. F., Birring, S. S., Blackhall, F., Bolser, D. C., Boulet, L. P., Braman, S. S., Brightling, C., Callahan-Lyon, P., Canning, B. J., Chang, A. B., Cowley, T., Davenport, P., ... Weir, K. (2017). Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer: CHEST Guideline and Expert Panel Report. Chest, 151(4), 861-874. https://doi.org/10.1016/j.chest.2016.12.028

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title = "Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer: CHEST Guideline and Expert Panel Report",

abstract = "We used a 2015 Cochrane systematic review, among other sources of evidence, to update the recommendations and suggestions of the American College of Chest Physicians (CHEST) 2006 guideline on this topic. Methods The CHEST methodologic guidelines and the Grading of Recommendations, Assessment, Development, and Evaluation framework were used. The Expert Cough Panel based their recommendations on data from the Cochrane systematic review on the topic, uncontrolled studies, case studies, and the clinical context. Final grading was reached by consensus according to the Delphi method. Results The Cochrane systematic review identified 17 trials of primarily low-quality evidence. Such evidence was related to both nonpharmacologic (cough suppression) and pharmacologic (demulcents, opioids, peripherally acting antitussives, or local anesthetics) treatments, as well as endobronchial brachytherapy. Conclusions Compared with the 2006 CHEST Cough Guideline, the current recommendations and suggestions are more specific and follow a step-up approach to the management of cough among patients with lung cancer, acknowledging the low-quality evidence in the field and the urgent need to develop more effective, evidence-based interventions through high-quality research.",

keywords = "cough, evidence-based medicine, guidelines, lung cancer",

author = "Alexandros Molasiotis and Smith, {Jaclyn A.} and Peter Mazzone and Fiona Blackhall and Irwin, {Richard S.} and Adams, {Todd M.} and Altman, {Kenneth W.} and Barker, {Alan F.} and Birring, {Surinder S.} and Fiona Blackhall and Bolser, {Donald C.} and Boulet, {Louis Philippe} and Braman, {Sidney S.} and Christopher Brightling and Priscilla Callahan-Lyon and Canning, {Brendan J.} and Chang, {Anne B.} and Terrie Cowley and Paul Davenport and Satoru Ebihara and {El Solh}, {Ali A.} and Patricio Escalante and Field, {Stephen K.} and Dina Fisher and French, {Cynthia T.} and Peter Gibson and Philip Gold and Cameron Grant and Anthony Harnden and Hill, {Adam T.} and Irwin, {Richard S.} and Kahrilas, {Peter J.} and Keogh, {Karina A.} and Kefang Lai and Lane, {Andrew P.} and Malesker, {Mark A.} and Peter Mazzone and Stuart Mazzone and Alex Molassiotis and Murad, {M. Hassan} and Peter Newcombe and Nguyen, {Huong Q.} and John Oppenheimer and Restrepo, {Marcos I.} and Mark Rosen and Bruce Rubin and Ryu, {Jay H.} and Jaclyn Smith and Tarlo, {Susan M.} and Julie Turmel and Vertigan, {Anne E.} and Weinberger, {Miles M.} and Kelly Weir",

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doi = "10.1016/j.chest.2016.12.028",

language = "English",

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pages = "861--874",

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Molasiotis, A, Smith, JA, Mazzone, P, Blackhall, F, Irwin, RS, Adams, TM, Altman, KW, Barker, AF, Birring, SS, Blackhall, F, Bolser, DC, Boulet, LP, Braman, SS, Brightling, C, Callahan-Lyon, P, Canning, BJ, Chang, AB, Cowley, T, Davenport, P, Ebihara, S, El Solh, AA, Escalante, P, Field, SK, Fisher, D, French, CT, Gibson, P, Gold, P, Grant, C, Harnden, A, Hill, AT, Irwin, RS, Kahrilas, PJ, Keogh, KA, Lai, K, Lane, AP, Malesker, MA, Mazzone, P, Mazzone, S, Molassiotis, A, Murad, MH, Newcombe, P, Nguyen, HQ, Oppenheimer, J, Restrepo, MI, Rosen, M, Rubin, B, Ryu, JH, Smith, J, Tarlo, SM, Turmel, J, Vertigan, AE, Weinberger, MM & Weir, K 2017, 'Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer: CHEST Guideline and Expert Panel Report', Chest, vol. 151, no. 4, pp. 861-874. https://doi.org/10.1016/j.chest.2016.12.028

TY - JOUR

T1 - Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer: CHEST Guideline and Expert Panel Report

AU - Molasiotis, Alexandros

AU - Smith, Jaclyn A.

AU - Mazzone, Peter

AU - Blackhall, Fiona

AU - Irwin, Richard S.

AU - Adams, Todd M.

AU - Altman, Kenneth W.

AU - Barker, Alan F.

AU - Birring, Surinder S.

AU - Blackhall, Fiona

AU - Bolser, Donald C.

AU - Boulet, Louis Philippe

AU - Braman, Sidney S.

AU - Brightling, Christopher

AU - Callahan-Lyon, Priscilla

AU - Canning, Brendan J.

AU - Chang, Anne B.

AU - Cowley, Terrie

AU - Davenport, Paul

AU - Ebihara, Satoru

AU - El Solh, Ali A.

AU - Escalante, Patricio

AU - Field, Stephen K.

AU - Fisher, Dina

AU - French, Cynthia T.

AU - Gibson, Peter

AU - Gold, Philip

AU - Grant, Cameron

AU - Harnden, Anthony

AU - Hill, Adam T.

AU - Irwin, Richard S.

AU - Kahrilas, Peter J.

AU - Keogh, Karina A.

AU - Lai, Kefang

AU - Lane, Andrew P.

AU - Malesker, Mark A.

AU - Mazzone, Peter

AU - Mazzone, Stuart

AU - Molassiotis, Alex

AU - Murad, M. Hassan

AU - Newcombe, Peter

AU - Nguyen, Huong Q.

AU - Oppenheimer, John

AU - Restrepo, Marcos I.

AU - Rosen, Mark

AU - Rubin, Bruce

AU - Ryu, Jay H.

AU - Smith, Jaclyn

AU - Tarlo, Susan M.

AU - Turmel, Julie

AU - Vertigan, Anne E.

AU - Weinberger, Miles M.

AU - Weir, Kelly

PY - 2017/4/1

Y1 - 2017/4/1

N2 - We used a 2015 Cochrane systematic review, among other sources of evidence, to update the recommendations and suggestions of the American College of Chest Physicians (CHEST) 2006 guideline on this topic. Methods The CHEST methodologic guidelines and the Grading of Recommendations, Assessment, Development, and Evaluation framework were used. The Expert Cough Panel based their recommendations on data from the Cochrane systematic review on the topic, uncontrolled studies, case studies, and the clinical context. Final grading was reached by consensus according to the Delphi method. Results The Cochrane systematic review identified 17 trials of primarily low-quality evidence. Such evidence was related to both nonpharmacologic (cough suppression) and pharmacologic (demulcents, opioids, peripherally acting antitussives, or local anesthetics) treatments, as well as endobronchial brachytherapy. Conclusions Compared with the 2006 CHEST Cough Guideline, the current recommendations and suggestions are more specific and follow a step-up approach to the management of cough among patients with lung cancer, acknowledging the low-quality evidence in the field and the urgent need to develop more effective, evidence-based interventions through high-quality research.

AB - We used a 2015 Cochrane systematic review, among other sources of evidence, to update the recommendations and suggestions of the American College of Chest Physicians (CHEST) 2006 guideline on this topic. Methods The CHEST methodologic guidelines and the Grading of Recommendations, Assessment, Development, and Evaluation framework were used. The Expert Cough Panel based their recommendations on data from the Cochrane systematic review on the topic, uncontrolled studies, case studies, and the clinical context. Final grading was reached by consensus according to the Delphi method. Results The Cochrane systematic review identified 17 trials of primarily low-quality evidence. Such evidence was related to both nonpharmacologic (cough suppression) and pharmacologic (demulcents, opioids, peripherally acting antitussives, or local anesthetics) treatments, as well as endobronchial brachytherapy. Conclusions Compared with the 2006 CHEST Cough Guideline, the current recommendations and suggestions are more specific and follow a step-up approach to the management of cough among patients with lung cancer, acknowledging the low-quality evidence in the field and the urgent need to develop more effective, evidence-based interventions through high-quality research.

KW - cough

KW - evidence-based medicine

KW - guidelines

KW - lung cancer

UR - http://www.scopus.com/inward/record.url?scp=85017156775&partnerID=8YFLogxK

U2 - 10.1016/j.chest.2016.12.028

DO - 10.1016/j.chest.2016.12.028

M3 - Journal article

C2 - 28108179

SN - 0012-3692

VL - 151

SP - 861

EP - 874

JO - Chest

JF - Chest

IS - 4

ER -

Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer: CHEST Guideline and Expert Panel Report

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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