Superhydrophobic/hydrophobic nanofibrous network with tunable cell adhesion: Fabrication, characterization and cellular activities

Fangyuan Dong, Mi Zhang, Wenyu Huang, Liping Zhou, Man Sau Wong, Yi Wang

Research output: Journal article publicationJournal articleAcademic researchpeer-review

12 Citations (Scopus)


Superhydrophobic/hydrophobic nanofibrous networks have attracted much attention because of their potential applications in tissue engineering. Cell growth in the scaffold of tissue engineering can be controlled by the hydrophobicity of the scaffold. The superhydrophobic/hydrophobic surfaces are usually made from synthesized polymers, which generally are not biocompatible and biodegradable and, thus, not suitable for biomedical applications. Zein is an amphiphilic protein from corn, and it is potential for hydrophobic surface formation. This work aims to make zein superhydrophobic/hydrophobic nanofibrous network using electrospinning. The formed zein networks show high hydrophobicity with the water contact angles ranging from 130.5 ± 1.0° to 153.6 ± 2.1°. The cell attachment and growth on the zein networks are studied. It is observed that the amount of the cells attached and grown in the zein nanofibrous networks are higher than the ones on the conventional zein casting films. The results indicate that the electrospun zein nanofibrous network has great potential as scaffold in tissue engineering to support cell growth and tissue regeneration.
Original languageEnglish
Pages (from-to)718-723
Number of pages6
JournalColloids and Surfaces A: Physicochemical and Engineering Aspects
Publication statusPublished - 5 Oct 2015


  • Cell adhesion
  • Electrospinning
  • Superhydrophobic
  • Zein

ASJC Scopus subject areas

  • Surfaces and Interfaces
  • Physical and Theoretical Chemistry
  • Colloid and Surface Chemistry


Dive into the research topics of 'Superhydrophobic/hydrophobic nanofibrous network with tunable cell adhesion: Fabrication, characterization and cellular activities'. Together they form a unique fingerprint.

Cite this