Abstract
The stochastic transfer function extends the concept of the conventional transfer function by incorporating noise statistics, thus giving a measure of the signal-to-noise ratio at each spatial frequency. This provides a convenient and standardized metric to assess the trade-off in terms of spatial frequency bandwidth and signalto-noise ratio for a diverse range of resolution enhancement techniques. We apply this concept to structured illumination microscopy and compare its noise performance as a function of frequency with the conventional wide-field fluorescent microscope. The result suggests how a hybrid algorithm further improves the photon efficiency of the structured illumination technique. © 2009 Optical Society of America.
Original language | English |
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Pages (from-to) | 1630-1637 |
Number of pages | 8 |
Journal | Journal of the Optical Society of America A: Optics and Image Science, and Vision |
Volume | 26 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1 Jul 2009 |
Externally published | Yes |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Computer Vision and Pattern Recognition