Stochastic transfer function for structured illumination microscopy

Michael Geoffrey Somekh, Ken Hsu, Mark C. Pitter

Research output: Journal article publicationJournal articleAcademic researchpeer-review

13 Citations (Scopus)

Abstract

The stochastic transfer function extends the concept of the conventional transfer function by incorporating noise statistics, thus giving a measure of the signal-to-noise ratio at each spatial frequency. This provides a convenient and standardized metric to assess the trade-off in terms of spatial frequency bandwidth and signalto-noise ratio for a diverse range of resolution enhancement techniques. We apply this concept to structured illumination microscopy and compare its noise performance as a function of frequency with the conventional wide-field fluorescent microscope. The result suggests how a hybrid algorithm further improves the photon efficiency of the structured illumination technique. © 2009 Optical Society of America.
Original languageEnglish
Pages (from-to)1630-1637
Number of pages8
JournalJournal of the Optical Society of America A: Optics and Image Science, and Vision
Volume26
Issue number7
DOIs
Publication statusPublished - 1 Jul 2009
Externally publishedYes

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Computer Vision and Pattern Recognition

Cite this