Stimulation of saponin production in Panax ginseng hairy roots by two oligosaccharides from Paris polyphylla var. yunnanensis

Ligang Zhou, Xiaodong Cao, Ruifen Zhang, Youliang Peng, Shoujing Zhao, Jianyong Wu

Research output: Journal article publicationJournal articleAcademic researchpeer-review

34 Citations (Scopus)


Two oligosaccharides, a heptasaccharide (HS) and an octasaccharide (OS), isolated from Paris polyphylla var. yunnanensis, stimulated the growth and saponin accumulation of Panax ginseng hairy roots at 5-30 mg l-1. HS and OS at 30 mg l-1, fed separately to hairy root cultures at 10 days post-inoculation, increased the root biomass dry weight by more than 70% to ∼20 g l-1from 13 g l-1and the total saponin content of roots by more than 1-fold to ∼3.5% from 1.6% (w/w). The results suggest that the two oligosaccharides may have plant growth-regulatory activity in plant tissue cultures.
Original languageEnglish
Pages (from-to)631-634
Number of pages4
JournalBiotechnology Letters
Issue number4
Publication statusPublished - 1 Apr 2007


  • Hairy root culture
  • Heptasaccharide
  • Octasaccharide
  • Oligosaccharides
  • Panax ginseng
  • Saponin

ASJC Scopus subject areas

  • Biotechnology

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