Abstract
(Matrix presented) Ruthenium porphyrins catalyze three-component coupling reaction of α-diazo esters with a series of N-benzylidene imines and alkenes to form functionalized pyrrolidines in excellent diastereoselectivities. The reaction proceeds via a reactive ruthenium-carbene intermediate and its subsequent reaction with imine to generate azomethine ylide, which reacts with alkenes via 1,3-diploar cycloaddition.
Original language | English |
---|---|
Pages (from-to) | 2153-2156 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 5 |
Issue number | 12 |
DOIs | |
Publication status | Published - 12 Jun 2003 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry