Abstract
Rhodium(III) porphyrin complexes [Rh(Por)Me] are catalytically active towards stereoselective intramolecular carbene C-H insertions of α-diazoacetamides to give cis-β-lactams or trans-γ-lactams in yields up to 99% with regioselectivities up to 100% and cis/trans ratios up to 83:17 for β-lactams.
Original language | English |
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Pages (from-to) | 2753-2757 |
Number of pages | 5 |
Journal | Synlett |
Volume | 23 |
Issue number | 19 |
DOIs | |
Publication status | Published - 22 Oct 2012 |
Keywords
- carbene C-H insertion
- intramolecular cyclization
- lactams
- rhodium porphyrin
- stereoselectivity
ASJC Scopus subject areas
- Organic Chemistry