TY - JOUR
T1 - Spreading-induced dewetting for monolayer colloidosomes with responsive permeability
AU - Lei, Leyan
AU - Tang, Xin
AU - Zhu, Pingan
AU - Kang, Zhanxiao
AU - Kong, Tiantian
AU - Wang, Liqiu
N1 - Funding Information:
Authors acknowledge the financial support received from the Research Grants Council of Hong Kong (GRF 17237316, 17211115, 17207914, HKU717613E), the University of Hong Kong (URC 201511159108, 201411159074 and 201311159187), the Young Scholar's Program (NSFC 11504238) from the National Natural Science Foundation of China, the Science and Technology Planning Project of Guangdong Province (2016A050503048), and the Fundamental Research Program of Shenzhen (JCYJ20160229164007864). The work was also supported in part by the Zhejiang Provincial, Hangzhou Municipal and Lin'an County Governments.
Publisher Copyright:
© 2017 The Royal Society of Chemistry.
PY - 2017
Y1 - 2017
N2 - Herein, we present a spreading-induced dewetting approach of Pickering emulsion droplets for fabricating monolayer colloidosomes. The dewetting of the water-in-oil-in-water (W/O/W) double emulsion droplets is triggered by the quick spreading and wetting of the fluorinated oil phase on the water/air surface. By combining this colloidosome formation mechanism with thermo-responsive copolymer that adsorbs or desorbs at the surface of the colloidosome shell, we fabricated smart monolayer colloidosomes using a microfluidic-templated approach. These colloidosomes are highly monodisperse and possess a well-defined shell microstructure, tunable permeability, biocompatibility, mechanical stability, and high encapsulation efficiency. These attributes will pave the way for effective encapsulation, transport, and release of a range of active ingredients, especially the biologically active materials.
AB - Herein, we present a spreading-induced dewetting approach of Pickering emulsion droplets for fabricating monolayer colloidosomes. The dewetting of the water-in-oil-in-water (W/O/W) double emulsion droplets is triggered by the quick spreading and wetting of the fluorinated oil phase on the water/air surface. By combining this colloidosome formation mechanism with thermo-responsive copolymer that adsorbs or desorbs at the surface of the colloidosome shell, we fabricated smart monolayer colloidosomes using a microfluidic-templated approach. These colloidosomes are highly monodisperse and possess a well-defined shell microstructure, tunable permeability, biocompatibility, mechanical stability, and high encapsulation efficiency. These attributes will pave the way for effective encapsulation, transport, and release of a range of active ingredients, especially the biologically active materials.
UR - http://www.scopus.com/inward/record.url?scp=85026818019&partnerID=8YFLogxK
U2 - 10.1039/c7tb01255a
DO - 10.1039/c7tb01255a
M3 - Journal article
C2 - 32264360
AN - SCOPUS:85026818019
SN - 2050-7518
VL - 5
SP - 6034
EP - 6041
JO - Journal of Materials Chemistry B
JF - Journal of Materials Chemistry B
IS - 30
ER -