Specific Activation of Photosensitizer with Extrinsic Enzyme for Precisive Photodynamic Therapy

Keyphrases

• β-Galactosidase (β-Gal) 100%
• Photosensitizer 100%
• Photodynamic Therapy 100%
• Tumor 66%
• Cancer Cells 66%
• O-phthalaldehyde 66%
• Laser Irradiation 33%
• Amines 33%
• Cyclization 33%
• Phenyl Group 33%
• Cell Death 33%
• Peptide Sequencing 33%
• One-pot Reaction 33%
• U87MG 33%
• Cysteine Residues 33%
• Multifunctional Protein 33%
• Nude Mice 33%
• High Specificity 33%
• Challenging Tasks 33%
• Photosensitizing 33%
• Therapeutic Use 33%
• Selective Delivery 33%
• Boron Dipyrromethene (BODIPY) 33%
• Galactose 33%
• Cyclic RGD 33%
• Tumor Site 33%
• Bifunctional Linker 33%
• Capture Reactions 33%
• Lock-and-key 33%
• Enzyme-activated 33%
• Self-immolative Linker 33%
• Intracellular Space 33%
• Self-immolation 33%
• Photodynamic Effect 33%
• Bromomethyl 33%
• Enzyme Modification 33%
• Bioconjugation Strategies 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Photodynamic Therapy 100%
• Photosensitizer 100%
• Neoplasm 75%
• Galactosidase 75%
• Malignant Neoplasm 50%
• Phthalaldehyde 50%
• Nude Mouse 25%
• Bioconjugation 25%
• Cysteine 25%
• Galactose 25%
• Phenyl Group 25%

Chemistry

• Galactosidase 100%