Solution processed low power organic field-effect transistor bio-chemical sensor of high transconductance efficiency

Wei Tang, Ying Fu, Yukun Huang, Yuanzhe Li, Yawen Song, Xin Xi, Yude Yu, Yuezeng Su, Feng Yan, Xiaojun Guo

Research output: Journal article publicationJournal articleAcademic researchpeer-review

26 Citations (Scopus)

Abstract

Developing organic field-effect transistor (OFET) biosensors for customizable detection of biomarkers for many diseases would provide a low-cost and convenient tool for both biological studies and clinical diagnosis. In this work, design principles of the OFET transducer for biosensors were derived to relate the signal-to-noise ratio (SNR) to the device-performance parameters. Steep subthreshold swing (SS), proper threshold voltage (Vth), good-enough bias-stress stability, and mechanical durability are shown to be the key prerequisites for realizing OFET bio-sensors of high transconductance efficiency (gm/ID) for large SNR. Combining a low trap-density channel and a high-k/low-k gate dielectric layer, low-temperature (<100 °C) solution-processed flexible OFETs can meet the performance requirements to maximize the gm/ID. An extended gate-structure OFET biosensor was further implemented for label-free detection of miR-21, achieving a detection limit below 10 pM with high selectivity at a low operation voltage (<1 V).

Original languageEnglish
Article number18
Journalnpj Flexible Electronics
Volume6
Issue number1
DOIs
Publication statusPublished - Mar 2022

ASJC Scopus subject areas

  • General Materials Science
  • Electrical and Electronic Engineering

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