Smartphone-Delivered Multicomponent Lifestyle Medicine Intervention for Depressive Symptoms: A Randomized Controlled Trial

Vincent Wing Hei Wong, Fiona Yan Yee Ho, Nga Kwan Shi, Jessica Tsz Yan Tong, Ka Fai Chung, Wing Fai Yeung, Chee H. Ng, Gina Oliver, Jerome Sarris

Research output: Journal article publicationJournal articleAcademic researchpeer-review

1 Citation (Scopus)


Objective: To evaluate the efficacy and credibility of a smartphone-delivered multicomponent lifestyle medicine (LM) intervention, Lifestyle Hub, as a primary modality for managing depressive symptoms in an adult Chinese population. Method: Participants with at least a moderate level of depressive symptoms (n = 79), as indicated by a Patient Health Questionnaire-9 score of ≥10, were randomly assigned to an LM intervention group (LMG; n = 39; eight weekly sessions) or a waitlist control group (WLG; n = 40). Results: The intention-to-treat analysis revealed significant improvements in depressive symptoms (d = 0.66), generalized anxiety symptoms (d = 0.93), insomnia symptoms (d = 0.20), functional impairment (d = 0.22), and health-related quality of life (HRQoL; d= 0.11) fromWeek 0 (baseline) toWeek 9 (immediate postintervention assessment) in the LMG relative to the WLG. Moreover, significantly more health-promoting behaviors (overall health behaviors, health responsibility, physical activity level, nutrition, spiritual growth, and stressmanagement) (d = 0.40–0.89) and higher levels of total activity (d = 0.55) and walking activity (d = 0.55) were found at Week 9 in the LMG relative to the WLG. However, no significant differences were observed in interpersonal relationships, vigorous and moderate exercise levels, sedentary behavior levels, or food frequency questionnaire measures atWeek 9 between the LMGand theWLG. From Week 9 to Week 13 (1-month follow-up assessment), a significant within-group reduction in HRQoL (d = 0.50) and an increase in alcohol intake (d = 0.41) were observed in the LMG. Conclusions: The smartphone-delivered multicomponent LM intervention Lifestyle Hub may serve as a primary modality for managing depressive symptoms.

Original languageEnglish
Pages (from-to)970-984
Number of pages15
JournalJournal of Consulting and Clinical Psychology
Issue number12
Publication statusPublished - Dec 2021


  • Lifestyle
  • Mood
  • Randomized controlled trial
  • Self-help
  • Smartphone-based intervention

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

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