Small circular oligodeoxynucleotides achieved from self-assembling entities

Dongsheng Liu, Jian Chen, Alex H.F. Lee, Ming Cheung Chow, Albert S.C. Chan, Tianhu Li

Research output: Journal article publicationJournal articleAcademic researchpeer-review

19 Citations (Scopus)


Self-recognition rather than complementarity defines the self-assembly (a) of two cytosine-rich oligodeoxynucleotides in the compact i-motif shown (C-C+base pairs, dark circles). When the 5′-terminal phosphate is activated, phosphodiester bonds form between the termini of the linear sequences, resulting in two circular oligodeoxynucleotides (b), which disassociate on denaturation (c).
Original languageEnglish
Pages (from-to)797-799
Number of pages3
JournalAngewandte Chemie - International Edition
Issue number7
Publication statusPublished - 17 Feb 2003


  • DNA structures
  • Oligonucleotides
  • Self-assembly

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)


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