Single-layer transition metal dichalcogenide nanosheet-based nanosensors for rapid, sensitive, and multiplexed detection of DNA

Ying Zhang, Bing Zheng, Changfeng Zhu, Xiao Zhang, Chaoliang Tan, Hai Li, Bo Chen, Jian Yang, Junze Chen, Ying Huang, Lianhui Wang, Hua Zhang

Research output: Journal article publicationJournal articleAcademic researchpeer-review

281 Citations (Scopus)


Single-layer transition metal dichalcogenide nanosheets, including MoS2, TiS2, and TaS2, are used as novel sensing platforms for sensitive and selective detection of DNA, based on their high fluorescence-quenching ability and different affinities toward single-stranded DNA and double-stranded DNA. Importantly, for the first time, a single-layer TaS2 nanosheet-based multiplexed DNA sensor is also developed.
Original languageEnglish
Pages (from-to)935-939
Number of pages5
JournalAdvanced Materials
Issue number5
Publication statusPublished - Feb 2015
Externally publishedYes

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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