Semiparametric estimation for regression coefficients in the cox model with failure indicators missing at random

Chunling Liu, Qihua Wang

Research output: Journal article publicationJournal articleAcademic researchpeer-review

7 Citations (Scopus)


This paper considers a regression imputation method for estimating the regression coefficients in the Cox model when some failure indicators are missing at random, and the conditional probability of the censoring indicator is assumed to be of a parametric form. To avoid problems with missspecification of the parametric form, two augmented inverse probability weighted estimators are defined, and their asymptotic properties are established. Simulation studies were conducted to demonstrate the performance of the proposed estimators, and a data set from a stage II breast cancer trial is used to illustrate our methods.
Original languageEnglish
Pages (from-to)1125-1142
Number of pages18
JournalStatistica Sinica
Issue number3
Publication statusPublished - 1 Jul 2010
Externally publishedYes


  • Augmented inverse probability weighting
  • Cox proportional hazards model
  • Missing at random
  • Nadaraya-Watson kernel estimate
  • Regression imputation

ASJC Scopus subject areas

  • Statistics and Probability
  • Statistics, Probability and Uncertainty

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