Abstract
Efficient methods for dioxirane-based selective C-H bond oxidation by supramolecular control in H 2O have been developed. With β-cyclodextrin as the supramolecular host, site-selective oxidation of the terminal over the internal tertiary C-H bond of 3,7-dimethyloctyl esters 3a-c was achieved. In addition, β-cyclodextrin selectively enhanced the C-H bond oxidation of cumene in a mixture of cumene and ethyl benzene in H 2O. Through 1H NMR studies, the selectivity in C-H bond oxidation could be attributed to the inclusion complex formation between β-cyclodextrin and the substrates.
Original language | English |
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Pages (from-to) | 3122-3130 |
Number of pages | 9 |
Journal | Organic and Biomolecular Chemistry |
Volume | 10 |
Issue number | 15 |
DOIs | |
Publication status | Published - 21 Apr 2012 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry