SARS-CoV-2 PROTEINS AND BIOTOXIN DETECTION USING PHOTONIC RESONATOR SENSOR

Binh T.T. Nguyen, Zhenyu Li, Hongwei Zhao, Xiaohong Zhou, Eric P.H. Yap, Yi Zhang, Ai Qun Liu

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

Abstract

The great advances in silicon photonic-sensing technology have made it an attractive platform for wide sensing applications. The small size of chip and detection system makes photonic microring resonator can be used in clinic for quick detection of disease. Here, we employ the high sensitivity of the photonic sensor toward the change of refractive index for the detection of SARS-CoV-2 virus spike proteins and botulinum toxin in water. The system require very small amount of sample 50uL with high sensitivity, in short 1hr without pre-treatment required. The measurement can be automatic with minimum manpower involved. Moreover, the system can be multiplexed to detect a few target analytes at the same time in one sample.

Original languageEnglish
Title of host publicationMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages1605-1606
Number of pages2
ISBN (Electronic)9781733419031
Publication statusPublished - Oct 2021
Externally publishedYes
Event25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, United States
Duration: 10 Oct 202114 Oct 2021

Publication series

NameMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Country/TerritoryUnited States
CityPalm Springs, Virtual
Period10/10/2114/10/21

Keywords

  • biotoxin
  • botulinum
  • photonic sensor
  • ring resonator
  • SARS-CoV-2 virus

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering (miscellaneous)

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