Abstract
(Matrix presented) A ruthenium porphyrin-catalyzed stereoselective intramolecular carbenoid C-H insertion is described. Using [RuII(TTP)(CO)] as catalyst, aryl tosylhydrazones are converted to 2,3-dihydrobenzofurans, 2,3-dihydroindoles, and β-lactams in good yields and remarkable cis selectivity (up to 99%). Enantioselective synthesis of 2,3-dihydrobenzofurans is also achieved with [RuII(D4-Por*)(CO)] as catalyst, and up to 96% ee is attained.
Original language | English |
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Pages (from-to) | 2535-2538 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 5 |
Issue number | 14 |
DOIs | |
Publication status | Published - 10 Jul 2003 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry