Abstract
[Chemical equation presented] A directing group-free approach for C2-selective carbenoid functionalization of NH-indoles is presented. Using [RuCl2(p-cymene)]2as catalyst and α-aryldiazoesters as carbenoid source, 2-alkylated indoles were obtained in up to 96% isolated yield. Similarly, a regioselective carbenoid functionalization of NH-pyrroles was also achieved.
Original language | English |
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Pages (from-to) | 604-607 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 12 |
Issue number | 3 |
DOIs | |
Publication status | Published - 5 Feb 2010 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry