Ruthenium catalyzed asymmetric transfer hydrogenation based on chiral P,N,O Schiff base ligands and crystal structure of a ruthenium(II) complex bearing chiral P,N,O Schiff base ligands

Hoi Lun Kwong; Wing Sze Lee; Tat Shing Lai; Wing Tak Wong

doi:10.1016/S1387-7003(99)00012-X

Ruthenium catalyzed asymmetric transfer hydrogenation based on chiral P,N,O Schiff base ligands and crystal structure of a ruthenium(II) complex bearing chiral P,N,O Schiff base ligands

Hoi Lun Kwong
, Wing Sze Lee
, Tat Shing Lai
, Wing Tak Wong

Research output: Journal article publication › Journal article › Academic research › peer-review

39 Citations (Scopus)

Abstract

A ruthenium catalyst, generated in situ by heating the chiral P,N,O Schiff base ligand L (L = (S)-Ph2PC6H4C=NCHPhCH2OH) with Ru(DMSO)4Cl2in 2-propanol, is active for asymmetric transfer hydrogenation with best enantioselectivity up to 81%. A ruthenium complex of formula RuL2Cl2is prepared and its crystal structure revealed that the two chiral P,N,O Schiff ligands are in meridional configuration. This complex is also an active catalyst for asymmetric transfer hydrogenation. However, the '[Ru(DMSO)4]Cl2+ chiral P,N,O ligand' protocol displays better enantioselectivity.

Original language	English
Pages (from-to)	66-69
Number of pages	4
Journal	Inorganic Chemistry Communications
Volume	2
Issue number	2
DOIs	https://doi.org/10.1016/S1387-7003(99)00012-X
Publication status	Published - 1 Jan 1999
Externally published	Yes

Keywords

Crystal structures
Ruthenium complexes
Schiff base ligand complexes

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Inorganic Chemistry
Materials Chemistry

More information

10.1016/S1387-7003(99)00012-X

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title = "Ruthenium catalyzed asymmetric transfer hydrogenation based on chiral P,N,O Schiff base ligands and crystal structure of a ruthenium(II) complex bearing chiral P,N,O Schiff base ligands",

abstract = "A ruthenium catalyst, generated in situ by heating the chiral P,N,O Schiff base ligand L (L = (S)-Ph2PC6H4C=NCHPhCH2OH) with Ru(DMSO)4Cl2in 2-propanol, is active for asymmetric transfer hydrogenation with best enantioselectivity up to 81\%. A ruthenium complex of formula RuL2Cl2is prepared and its crystal structure revealed that the two chiral P,N,O Schiff ligands are in meridional configuration. This complex is also an active catalyst for asymmetric transfer hydrogenation. However, the '[Ru(DMSO)4]Cl2+ chiral P,N,O ligand' protocol displays better enantioselectivity.",

keywords = "Crystal structures, Ruthenium complexes, Schiff base ligand complexes",

author = "Kwong, \{Hoi Lun\} and Lee, \{Wing Sze\} and Lai, \{Tat Shing\} and Wong, \{Wing Tak\}",

year = "1999",

month = jan,

day = "1",

doi = "10.1016/S1387-7003(99)00012-X",

language = "English",

volume = "2",

pages = "66--69",

journal = "Inorganic Chemistry Communications",

issn = "1387-7003",

publisher = "Elsevier B.V.",

number = "2",

}

Ruthenium catalyzed asymmetric transfer hydrogenation based on chiral P,N,O Schiff base ligands and crystal structure of a ruthenium(II) complex bearing chiral P,N,O Schiff base ligands. / Kwong, Hoi Lun; Lee, Wing Sze; Lai, Tat Shing et al.
In: Inorganic Chemistry Communications, Vol. 2, No. 2, 01.01.1999, p. 66-69.

Research output: Journal article publication › Journal article › Academic research › peer-review

TY - JOUR

T1 - Ruthenium catalyzed asymmetric transfer hydrogenation based on chiral P,N,O Schiff base ligands and crystal structure of a ruthenium(II) complex bearing chiral P,N,O Schiff base ligands

AU - Kwong, Hoi Lun

AU - Lee, Wing Sze

AU - Lai, Tat Shing

AU - Wong, Wing Tak

PY - 1999/1/1

Y1 - 1999/1/1

N2 - A ruthenium catalyst, generated in situ by heating the chiral P,N,O Schiff base ligand L (L = (S)-Ph2PC6H4C=NCHPhCH2OH) with Ru(DMSO)4Cl2in 2-propanol, is active for asymmetric transfer hydrogenation with best enantioselectivity up to 81%. A ruthenium complex of formula RuL2Cl2is prepared and its crystal structure revealed that the two chiral P,N,O Schiff ligands are in meridional configuration. This complex is also an active catalyst for asymmetric transfer hydrogenation. However, the '[Ru(DMSO)4]Cl2+ chiral P,N,O ligand' protocol displays better enantioselectivity.

AB - A ruthenium catalyst, generated in situ by heating the chiral P,N,O Schiff base ligand L (L = (S)-Ph2PC6H4C=NCHPhCH2OH) with Ru(DMSO)4Cl2in 2-propanol, is active for asymmetric transfer hydrogenation with best enantioselectivity up to 81%. A ruthenium complex of formula RuL2Cl2is prepared and its crystal structure revealed that the two chiral P,N,O Schiff ligands are in meridional configuration. This complex is also an active catalyst for asymmetric transfer hydrogenation. However, the '[Ru(DMSO)4]Cl2+ chiral P,N,O ligand' protocol displays better enantioselectivity.

KW - Crystal structures

KW - Ruthenium complexes

KW - Schiff base ligand complexes

UR - https://www.scopus.com/pages/publications/0033434461

U2 - 10.1016/S1387-7003(99)00012-X

DO - 10.1016/S1387-7003(99)00012-X

M3 - Journal article

SN - 1387-7003

VL - 2

SP - 66

EP - 69

JO - Inorganic Chemistry Communications

JF - Inorganic Chemistry Communications

IS - 2

ER -

Ruthenium catalyzed asymmetric transfer hydrogenation based on chiral P,N,O Schiff base ligands and crystal structure of a ruthenium(II) complex bearing chiral P,N,O Schiff base ligands

Abstract

Keywords

ASJC Scopus subject areas

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