Ring-closing metathesis in the synthesis of BC ring-systems of taxol

Cong Ma; Stéphanie Schiltz; Xavier F. Le Goff; Joëlle Prunet

doi:10.1002/chem.200800774

Ring-closing metathesis in the synthesis of BC ring-systems of taxol

Cong Ma, Stéphanie Schiltz, Xavier F. Le Goff, Joëlle Prunet

Research output: Journal article publication › Journal article › Academic research › peer-review

29 Citations (Scopus)

Abstract

BC ring-systems of taxol with different or no protecting group for the C1,C2-diol moiety have been efficiently synthesized. The eight-membered B ring is formed by a ring-closing metathesis reaction (RCM) between the C10 and C11 carbon atoms. The influence of the 1,2-diol protecting group on the RCM reaction has been studied in detail. KGaA,.

Original language	English
Pages (from-to)	7314-7323
Number of pages	10
Journal	Chemistry - A European Journal
Volume	14
Issue number	24
DOIs	https://doi.org/10.1002/chem.200800774
Publication status	Published - 18 Aug 2008
Externally published	Yes

Keywords

Metathesis
Organic chemistry
Ruthenium
Synthesis
Taxol

ASJC Scopus subject areas

Chemistry(all)

More information

10.1002/chem.200800774

Scopus Link

Cite this

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abstract = "BC ring-systems of taxol with different or no protecting group for the C1,C2-diol moiety have been efficiently synthesized. The eight-membered B ring is formed by a ring-closing metathesis reaction (RCM) between the C10 and C11 carbon atoms. The influence of the 1,2-diol protecting group on the RCM reaction has been studied in detail. KGaA,.",

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AU - Le Goff, Xavier F.

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KW - Metathesis

KW - Organic chemistry

KW - Ruthenium

KW - Synthesis

KW - Taxol

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DO - 10.1002/chem.200800774

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