Rhodium(III)-catalyzed intermolecular direct amination of aromatic C-H bonds with N-chloroamines

Ka Ho Ng, Zhongyuan Zhou, Wing Yiu Yu

Research output: Journal article publicationJournal articleAcademic researchpeer-review

183 Citations (Scopus)

Abstract

A Rh(III)-catalyzed direct aromatic C-H amination is achieved using N-chloroamines as a reagent. Furthermore, we also developed a one-pot amination protocol involving in situ chlorination of the secondary amines. The catalytic amination operates at mild conditions with excellent functional group tolerance and regioselectivity.
Original languageEnglish
Pages (from-to)272-275
Number of pages4
JournalOrganic Letters
Volume14
Issue number1
DOIs
Publication statusPublished - 6 Jan 2012

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this