Review: Hemodynamic studies for lower limb amputation and rehabilitation

Ruiqi Dong, Wentao Jiang, Ming Zhang, Kam Lun Leung, Man Sang Wong

Research output: Journal article publicationReview articleAcademic researchpeer-review

3 Citations (Scopus)


No matter what the reason and level of amputation are, amputees will face many complex postoperative problems and potential complications. From the perioperative stage to lengthy rehabilitation process, patients need comprehensive and cautious therapies to help them rebuild their physical and mental health. Although there is some scattered information, the achievements of hemodynamic study for lower limb amputation and rehabilitation have not been systematically classified and summarized. The purpose of this review is to introduce and discuss the hemodynamic issues in preoperative diagnosis, surgical techniques and postoperative problems in the past two decades. Whether from clinical or biomechanical perspective, the investigations of the former two stages have been relatively mature and gained some clear outcomes, even if some conclusions are conflicting and controversial. While in terms of the postoperative problems, such as the common pressure ulcers, DTI and muscle atrophy, there is a lack of vascular or blood flow state studies specifically for lower residual limb. Therefore, the future research focus of hemodynamics for lower limb amputation should probably be the detailed investigations on the relationships between various blood flow parameters and certain common complications. Although hemodynamic research has made some achievements at this stage, it is believed that more advanced and reliable techniques are pending for further explorations and developments.
Original languageEnglish
Article number1530005
JournalJournal of Mechanics in Medicine and Biology
Issue number4
Publication statusPublished - 1 Jan 2015


  • Amputation
  • blood flow
  • deep tissue injury
  • ischemia
  • lower limb
  • muscle atrophy
  • preoperative assessment
  • pressure ulcer
  • rehabilitation
  • residual limb
  • surgical techniques
  • vascular
  • vessels

ASJC Scopus subject areas

  • Biomedical Engineering


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