Retinal vessel centerline extraction using multiscale matched filter and sparse representation-based classifier

Bob Zhang, Qin Li, Lei Zhang, Jia You, Fakhri Karray

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

3 Citations (Scopus)


Retina located in the back of the eye contains useful information in the diagnosis of certain diseases. By locating a blood vessel's width, color, reflectivity, tortuosity and abnormal branching, one can deduce the existence of these diseases. In order for this to be achieved, blood vessels first need to be extracted from its background in fundus image. In this paper we propose a new method to extract vessels based on Multiscale Production of Matched Filter (MPMF) and Sparse Representation-based Classifier (SRC). First, we locate vessel centerline candidates using multi-scale Gaussian filtering, scale production, double thresholding and centerline detection. Then, the candidates which are centerline pixels are classified with SRC. Particularly, two dictionary elements of vessel and non-vessel are used in the SRC process. Experimental results on two public databases show that the proposed method is good at distinguishing vessel from non-vessel objects and extracting the centerlines of small vessels.
Original languageEnglish
Title of host publicationMedical Biometrics - Second International Conference, ICMB 2010, Proceedings
Number of pages10
Publication statusPublished - 21 Jul 2010
Event2nd International Conference on Medical Biometrics, ICMB 2010 - Hong Kong, Hong Kong
Duration: 28 Jun 201030 Jun 2010

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume6165 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349


Conference2nd International Conference on Medical Biometrics, ICMB 2010
Country/TerritoryHong Kong
CityHong Kong


  • Matched Filter
  • multiscale Gaussian filtering
  • retinal vessel
  • Sparse Representation-based Classifier

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

Cite this