Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

Ga Lai Law; Robert Pal; Lars O. Palsson; David Parker; Ka Leung Wong

doi:10.1039/b920222f

Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

Ga Lai Law
, Robert Pal
, Lars O. Palsson
, David Parker
, Ka Leung Wong

Research output: Journal article publication › Journal article › Academic research › peer-review

114 Citations (Scopus)

Abstract

A terbium complex has been designed that may be used to sensitise formation of singlet oxygen (_em 12%), allowing the creation of a ratiometric sensory system for pO₂ (versus the insensitive Eu analogue) and the definition of a reactive probe that can be used to cause local damage to cells loaded with the complex and exposed to laser excitation.

Original language	English
Pages (from-to)	7321-7323
Number of pages	3
Journal	Chemical Communications
Issue number	47
DOIs	https://doi.org/10.1039/b920222f
Publication status	Published - 30 Dec 2009
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b920222f

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title = "Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing",

abstract = "A terbium complex has been designed that may be used to sensitise formation of singlet oxygen (em 12\%), allowing the creation of a ratiometric sensory system for pO2 (versus the insensitive Eu analogue) and the definition of a reactive probe that can be used to cause local damage to cells loaded with the complex and exposed to laser excitation.",

author = "Law, \{Ga Lai\} and Robert Pal and Palsson, \{Lars O.\} and David Parker and Wong, \{Ka Leung\}",

year = "2009",

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Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing. / Law, Ga Lai; Pal, Robert; Palsson, Lars O. et al.
In: Chemical Communications, No. 47, 30.12.2009, p. 7321-7323.

Research output: Journal article publication › Journal article › Academic research › peer-review

TY - JOUR

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AU - Pal, Robert

AU - Palsson, Lars O.

AU - Parker, David

AU - Wong, Ka Leung

PY - 2009/12/30

Y1 - 2009/12/30

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AB - A terbium complex has been designed that may be used to sensitise formation of singlet oxygen (em 12%), allowing the creation of a ratiometric sensory system for pO2 (versus the insensitive Eu analogue) and the definition of a reactive probe that can be used to cause local damage to cells loaded with the complex and exposed to laser excitation.

UR - https://www.scopus.com/pages/publications/72649102984

U2 - 10.1039/b920222f

DO - 10.1039/b920222f

M3 - Journal article

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JO - Chemical Communications

JF - Chemical Communications

IS - 47

ER -

Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

Abstract

ASJC Scopus subject areas

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